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Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Bhardwaj R, Lindinger S, Neuberger A, Nadezhdin KD, Singh AK, Cunha MR, Derler I, Gyimesi G, Reymond JL, Hediger MA, Romanin C, Sobolevsky AI. Bhardwaj R, et al. Among authors: neuberger a. Sci Adv. 2020 Nov 27;6(48):eabe1508. doi: 10.1126/sciadv.abe1508. Print 2020 Nov. Sci Adv. 2020. PMID: 33246965 Free PMC article.
Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nadezhdin KD, Neuberger A, Trofimov YA, Krylov NA, Sinica V, Kupko N, Vlachova V, Zakharian E, Efremov RG, Sobolevsky AI. Nadezhdin KD, et al. Among authors: neuberger a. Nat Struct Mol Biol. 2021 Jul;28(7):564-572. doi: 10.1038/s41594-021-00615-4. Epub 2021 Jul 8. Nat Struct Mol Biol. 2021. PMID: 34239124 Free PMC article.
Human TRPV1 structure and inhibition by the analgesic SB-366791.
Neuberger A, Oda M, Nikolaev YA, Nadezhdin KD, Gracheva EO, Bagriantsev SN, Sobolevsky AI. Neuberger A, et al. Nat Commun. 2023 Apr 28;14(1):2451. doi: 10.1038/s41467-023-38162-9. Nat Commun. 2023. PMID: 37117175 Free PMC article.
Structural mechanisms of TRPM7 activation and inhibition.
Nadezhdin KD, Correia L, Narangoda C, Patel DS, Neuberger A, Gudermann T, Kurnikova MG, Chubanov V, Sobolevsky AI. Nadezhdin KD, et al. Among authors: neuberger a. Nat Commun. 2023 May 8;14(1):2639. doi: 10.1038/s41467-023-38362-3. Nat Commun. 2023. PMID: 37156763 Free PMC article.
291 results