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Perturbing the energy landscape for improved packing during computational protein design.
Maguire JB, Haddox HK, Strickland D, Halabiya SF, Coventry B, Griffin JR, Pulavarti SVSRK, Cummins M, Thieker DF, Klavins E, Szyperski T, DiMaio F, Baker D, Kuhlman B. Maguire JB, et al. Among authors: klavins e. Proteins. 2021 Apr;89(4):436-449. doi: 10.1002/prot.26030. Epub 2020 Dec 11. Proteins. 2021. PMID: 33249652 Free PMC article.
Aquarium: open-source laboratory software for design, execution and data management.
Vrana J, de Lange O, Yang Y, Newman G, Saleem A, Miller A, Cordray C, Halabiya S, Parks M, Lopez E, Goldberg S, Keller B, Strickland D, Klavins E. Vrana J, et al. Among authors: klavins e. Synth Biol (Oxf). 2021 Jan 30;6(1):ysab006. doi: 10.1093/synbio/ysab006. eCollection 2021. Synth Biol (Oxf). 2021. PMID: 34151028 Free PMC article.
Large-scale design and refinement of stable proteins using sequence-only models.
Singer JM, Novotney S, Strickland D, Haddox HK, Leiby N, Rocklin GJ, Chow CM, Roy A, Bera AK, Motta FC, Cao L, Strauch EM, Chidyausiku TM, Ford A, Ho E, Zaitzeff A, Mackenzie CO, Eramian H, DiMaio F, Grigoryan G, Vaughn M, Stewart LJ, Baker D, Klavins E. Singer JM, et al. Among authors: klavins e. PLoS One. 2022 Mar 14;17(3):e0265020. doi: 10.1371/journal.pone.0265020. eCollection 2022. PLoS One. 2022. PMID: 35286324 Free PMC article.
Synthetic Bistability and Differentiation in Yeast.
Yang Y, Nemhauser JL, Klavins E. Yang Y, et al. Among authors: klavins e. ACS Synth Biol. 2019 May 17;8(5):929-936. doi: 10.1021/acssynbio.8b00524. Epub 2019 May 1. ACS Synth Biol. 2019. PMID: 31021593 Free PMC article.
An improved autonomous DNA nanomotor.
Bishop JD, Klavins E. Bishop JD, et al. Among authors: klavins e. Nano Lett. 2007 Sep;7(9):2574-7. doi: 10.1021/nl070752s. Epub 2007 Jul 26. Nano Lett. 2007. PMID: 17655267
Fine-tuning gene networks using simple sequence repeats.
Egbert RG, Klavins E. Egbert RG, et al. Among authors: klavins e. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16817-22. doi: 10.1073/pnas.1205693109. Epub 2012 Aug 27. Proc Natl Acad Sci U S A. 2012. PMID: 22927382 Free PMC article.
Recapitulation of the forward nuclear auxin response pathway in yeast.
Pierre-Jerome E, Jang SS, Havens KA, Nemhauser JL, Klavins E. Pierre-Jerome E, et al. Among authors: klavins e. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9407-12. doi: 10.1073/pnas.1324147111. Epub 2014 Jun 16. Proc Natl Acad Sci U S A. 2014. PMID: 24979769 Free PMC article.
30 results