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Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility.
Hayase Y, Amano S, Hashizume K, Tominaga T, Miyamoto H, Kanno Y, Ueno-Inoue Y, Inoue T, Yamada M, Ogata S, Balan S, Hayashi K, Miura Y, Tokudome K, Ohno Y, Nishijo T, Momiyama T, Yanagawa Y, Takizawa A, Mashimo T, Serikawa T, Sekine A, Nakagawa E, Takeshita E, Yoshikawa T, Waga C, Inoue K, Goto YI, Nabeshima Y, Ihara N, Yamakawa K, Taya S, Hoshino M. Hayase Y, et al. Among authors: miyamoto h. Acta Neuropathol Commun. 2020 Nov 30;8(1):206. doi: 10.1186/s40478-020-01082-6. Acta Neuropathol Commun. 2020. PMID: 33256836 Free PMC article.
Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.
Ogiwara I, Miyamoto H, Morita N, Atapour N, Mazaki E, Inoue I, Takeuchi T, Itohara S, Yanagawa Y, Obata K, Furuichi T, Hensch TK, Yamakawa K. Ogiwara I, et al. Among authors: miyamoto h. J Neurosci. 2007 May 30;27(22):5903-14. doi: 10.1523/JNEUROSCI.5270-06.2007. J Neurosci. 2007. PMID: 17537961 Free PMC article.
Efhc1 deficiency causes spontaneous myoclonus and increased seizure susceptibility.
Suzuki T, Miyamoto H, Nakahari T, Inoue I, Suemoto T, Jiang B, Hirota Y, Itohara S, Saido TC, Tsumoto T, Sawamoto K, Hensch TK, Delgado-Escueta AV, Yamakawa K. Suzuki T, et al. Among authors: miyamoto h. Hum Mol Genet. 2009 Mar 15;18(6):1099-109. doi: 10.1093/hmg/ddp006. Epub 2009 Jan 15. Hum Mol Genet. 2009. PMID: 19147686 Free PMC article.
Elfn1 recruits presynaptic mGluR7 in trans and its loss results in seizures.
Tomioka NH, Yasuda H, Miyamoto H, Hatayama M, Morimura N, Matsumoto Y, Suzuki T, Odagawa M, Odaka YS, Iwayama Y, Won Um J, Ko J, Inoue Y, Kaneko S, Hirose S, Yamada K, Yoshikawa T, Yamakawa K, Aruga J. Tomioka NH, et al. Among authors: miyamoto h. Nat Commun. 2014 Jul 22;5:4501. doi: 10.1038/ncomms5501. Nat Commun. 2014. PMID: 25047565 Free article.
Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.
Ogiwara I, Miyamoto H, Tatsukawa T, Yamagata T, Nakayama T, Atapour N, Miura E, Mazaki E, Ernst SJ, Cao D, Ohtani H, Itohara S, Yanagawa Y, Montal M, Yuzaki M, Inoue Y, Hensch TK, Noebels JL, Yamakawa K. Ogiwara I, et al. Among authors: miyamoto h. Commun Biol. 2018;1:96. doi: 10.1038/s42003-018-0099-2. Epub 2018 Jul 19. Commun Biol. 2018. PMID: 30175250 Free PMC article.
Impaired cortico-striatal excitatory transmission triggers epilepsy.
Miyamoto H, Tatsukawa T, Shimohata A, Yamagata T, Suzuki T, Amano K, Mazaki E, Raveau M, Ogiwara I, Oba-Asaka A, Hensch TK, Itohara S, Sakimura K, Kobayashi K, Kobayashi K, Yamakawa K. Miyamoto H, et al. Nat Commun. 2019 Apr 23;10(1):1917. doi: 10.1038/s41467-019-09954-9. Nat Commun. 2019. PMID: 31015467 Free PMC article.
1,879 results