Gutteridge A - Search Results

1

Network and pathway expansion of genetic disease associations identifies successful drug targets.

MacNamara A, Nakic N, Amin Al Olama A, Guo C, Sieber KB, Hurle MR, Gutteridge A. MacNamara A, et al. Among authors: gutteridge a. Sci Rep. 2020 Dec 1;10(1):20970. doi: 10.1038/s41598-020-77847-9. Sci Rep. 2020. PMID: 33262371 Free PMC article.

2

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases.

Zheng J, Haberland V, Baird D, Walker V, Haycock PC, Hurle MR, Gutteridge A, Erola P, Liu Y, Luo S, Robinson J, Richardson TG, Staley JR, Elsworth B, Burgess S, Sun BB, Danesh J, Runz H, Maranville JC, Martin HM, Yarmolinsky J, Laurin C, Holmes MV, Liu JZ, Estrada K, Santos R, McCarthy L, Waterworth D, Nelson MR, Smith GD, Butterworth AS, Hemani G, Scott RA, Gaunt TR. Zheng J, et al. Among authors: gutteridge a. Nat Genet. 2020 Oct;52(10):1122-1131. doi: 10.1038/s41588-020-0682-6. Epub 2020 Sep 7. Nat Genet. 2020. PMID: 32895551 Free PMC article.

3

Using transfer learning from prior reference knowledge to improve the clustering of single-cell RNA-Seq data.

Mieth B, Hockley JRF, Görnitz N, Vidovic MM, Müller KR, Gutteridge A, Ziemek D. Mieth B, et al. Among authors: gutteridge a. Sci Rep. 2019 Dec 30;9(1):20353. doi: 10.1038/s41598-019-56911-z. Sci Rep. 2019. PMID: 31889137 Free PMC article.

4

Benchmarking network propagation methods for disease gene identification.

Picart-Armada S, Barrett SJ, Willé DR, Perera-Lluna A, Gutteridge A, Dessailly BH. Picart-Armada S, et al. Among authors: gutteridge a. PLoS Comput Biol. 2019 Sep 3;15(9):e1007276. doi: 10.1371/journal.pcbi.1007276. eCollection 2019 Sep. PLoS Comput Biol. 2019. PMID: 31479437 Free PMC article.

5

GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.

Jones AV, Tilley M, Gutteridge A, Hyde C, Nagle M, Ziemek D, Gorman D, Fauman EB, Chen X, Miller MR, Tian C, Hu Y, Hinds DA, Cox P, Scollen S. Jones AV, et al. Among authors: gutteridge a. Hum Mol Genet. 2017 Apr 1;26(7):1391-1406. doi: 10.1093/hmg/ddx036. Hum Mol Genet. 2017. PMID: 28199695 Free PMC article.

6

Novel pancreatic endocrine maturation pathways identified by genomic profiling and causal reasoning.

Gutteridge A, Rukstalis JM, Ziemek D, Tié M, Ji L, Ramos-Zayas R, Nardone NA, Norquay LD, Brenner MB, Tang K, McNeish JD, Rowntree RK. Gutteridge A, et al. PLoS One. 2013;8(2):e56024. doi: 10.1371/journal.pone.0056024. Epub 2013 Feb 13. PLoS One. 2013. PMID: 23418498 Free PMC article.

7

Single-cell RNAseq reveals seven classes of colonic sensory neuron.

Hockley JRF, Taylor TS, Callejo G, Wilbrey AL, Gutteridge A, Bach K, Winchester WJ, Bulmer DC, McMurray G, Smith ESJ. Hockley JRF, et al. Among authors: gutteridge a. Gut. 2019 Apr;68(4):633-644. doi: 10.1136/gutjnl-2017-315631. Epub 2018 Feb 26. Gut. 2019. PMID: 29483303 Free PMC article.

8

Molecular causes of transcriptional response: a Bayesian prior knowledge approach.

Zarringhalam K, Enayetallah A, Gutteridge A, Sidders B, Ziemek D. Zarringhalam K, et al. Among authors: gutteridge a. Bioinformatics. 2013 Dec 15;29(24):3167-73. doi: 10.1093/bioinformatics/btt557. Epub 2013 Sep 26. Bioinformatics. 2013. PMID: 24078682 Free PMC article.

9

Interpreting transcriptional changes using causal graphs: new methods and their practical utility on public networks.

Fakhry CT, Choudhary P, Gutteridge A, Sidders B, Chen P, Ziemek D, Zarringhalam K. Fakhry CT, et al. Among authors: gutteridge a. BMC Bioinformatics. 2016 Aug 24;17(1):318. doi: 10.1186/s12859-016-1181-8. BMC Bioinformatics. 2016. PMID: 27553489 Free PMC article.

10

Molecular and functional variation in iPSC-derived sensory neurons.

Schwartzentruber J, Foskolou S, Kilpinen H, Rodrigues J, Alasoo K, Knights AJ, Patel M, Goncalves A, Ferreira R, Benn CL, Wilbrey A, Bictash M, Impey E, Cao L, Lainez S, Loucif AJ, Whiting PJ; HIPSCI Consortium; Gutteridge A, Gaffney DJ. Schwartzentruber J, et al. Among authors: gutteridge a. Nat Genet. 2018 Jan;50(1):54-61. doi: 10.1038/s41588-017-0005-8. Epub 2017 Dec 11. Nat Genet. 2018. PMID: 29229984 Free PMC article.

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