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Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability.
King AJ, Siegel M, He Y, Nie B, Wang J, Koo-McCoy S, Minassian NA, Jafri Q, Pan D, Kohler J, Kumaraswamy P, Kozuka K, Lewis JG, Dragoli D, Rosenbaum DP, O'Neill D, Plain A, Greasley PJ, Jönsson-Rylander AC, Karlsson D, Behrendt M, Strömstedt M, Ryden-Bergsten T, Knöpfel T, Pastor Arroyo EM, Hernando N, Marks J, Donowitz M, Wagner CA, Alexander RT, Caldwell JS. King AJ, et al. Among authors: kumaraswamy p. Sci Transl Med. 2018 Aug 29;10(456):eaam6474. doi: 10.1126/scitranslmed.aam6474. Sci Transl Med. 2018. PMID: 30158152 Free PMC article. Clinical Trial.
Evaluation of the Pharmacodynamic Effects of the Potassium Binder RDX7675 in Mice.
Davidson JP, King AJ, Kumaraswamy P, Caldwell JS, Korner P, Blanks RC, Jacobs JW. Davidson JP, et al. Among authors: kumaraswamy p. J Cardiovasc Pharmacol Ther. 2018 May;23(3):244-253. doi: 10.1177/1074248417741685. Epub 2017 Nov 12. J Cardiovasc Pharmacol Ther. 2018. PMID: 29130735 Free PMC article.
Development and Characterization of a Human and Mouse Intestinal Epithelial Cell Monolayer Platform.
Kozuka K, He Y, Koo-McCoy S, Kumaraswamy P, Nie B, Shaw K, Chan P, Leadbetter M, He L, Lewis JG, Zhong Z, Charmot D, Balaa M, King AJ, Caldwell JS, Siegel M. Kozuka K, et al. Among authors: kumaraswamy p. Stem Cell Reports. 2017 Dec 12;9(6):1976-1990. doi: 10.1016/j.stemcr.2017.10.013. Epub 2017 Nov 16. Stem Cell Reports. 2017. PMID: 29153987 Free PMC article.
21 results