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Stabilizing the HIV-1 envelope glycoprotein State 2A conformation.
Vézina D, Gong SY, Tolbert WD, Ding S, Nguyen D, Richard J, Gendron-Lepage G, Melillo B 3rd, Smith AB, Pazgier M, Finzi A. Vézina D, et al. Among authors: pazgier m. J Virol. 2021 Mar 1;95(5):e01620-20. doi: 10.1128/JVI.01620-20. Epub 2020 Dec 9. J Virol. 2021. PMID: 33298541 Free PMC article.
Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection.
Acharya P, Tolbert WD, Gohain N, Wu X, Yu L, Liu T, Huang W, Huang CC, Kwon YD, Louder RK, Luongo TS, McLellan JS, Pancera M, Yang Y, Zhang B, Flinko R, Foulke JS Jr, Sajadi MM, Kamin-Lewis R, Robinson JE, Martin L, Kwong PD, Guan Y, DeVico AL, Lewis GK, Pazgier M. Acharya P, et al. Among authors: pazgier m. J Virol. 2014 Nov;88(21):12895-906. doi: 10.1128/JVI.02194-14. Epub 2014 Aug 27. J Virol. 2014. PMID: 25165110 Free PMC article.
CD4 mimetics sensitize HIV-1-infected cells to ADCC.
Richard J, Veillette M, Brassard N, Iyer SS, Roger M, Martin L, Pazgier M, Schön A, Freire E, Routy JP, Smith AB 3rd, Park J, Jones DM, Courter JR, Melillo BN, Kaufmann DE, Hahn BH, Permar SR, Haynes BF, Madani N, Sodroski JG, Finzi A. Richard J, et al. Among authors: pazgier m. Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2687-94. doi: 10.1073/pnas.1506755112. Epub 2015 May 4. Proc Natl Acad Sci U S A. 2015. PMID: 25941367 Free PMC article.
Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1.
Gohain N, Tolbert WD, Acharya P, Yu L, Liu T, Zhao P, Orlandi C, Visciano ML, Kamin-Lewis R, Sajadi MM, Martin L, Robinson JE, Kwong PD, DeVico AL, Ray K, Lewis GK, Pazgier M. Gohain N, et al. Among authors: pazgier m. J Virol. 2015 Sep;89(17):8840-54. doi: 10.1128/JVI.01232-15. Epub 2015 Jun 17. J Virol. 2015. PMID: 26085162 Free PMC article.
A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies.
Ding S, Veillette M, Coutu M, Prévost J, Scharf L, Bjorkman PJ, Ferrari G, Robinson JE, Stürzel C, Hahn BH, Sauter D, Kirchhoff F, Lewis GK, Pazgier M, Finzi A. Ding S, et al. Among authors: pazgier m. J Virol. 2015 Dec 4;90(4):2127-34. doi: 10.1128/JVI.02779-15. Print 2016 Feb 15. J Virol. 2015. PMID: 26637462 Free PMC article.
Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region.
Tolbert WD, Gohain N, Veillette M, Chapleau JP, Orlandi C, Visciano ML, Ebadi M, DeVico AL, Fouts TR, Finzi A, Lewis GK, Pazgier M. Tolbert WD, et al. Among authors: pazgier m. Structure. 2016 May 3;24(5):697-709. doi: 10.1016/j.str.2016.03.005. Epub 2016 Mar 31. Structure. 2016. PMID: 27041594 Free PMC article.
Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins.
Richard J, Pacheco B, Gohain N, Veillette M, Ding S, Alsahafi N, Tolbert WD, Prévost J, Chapleau JP, Coutu M, Jia M, Brassard N, Park J, Courter JR, Melillo B, Martin L, Tremblay C, Hahn BH, Kaufmann DE, Wu X, Smith AB 3rd, Sodroski J, Pazgier M, Finzi A. Richard J, et al. Among authors: pazgier m. EBioMedicine. 2016 Oct;12:208-218. doi: 10.1016/j.ebiom.2016.09.004. Epub 2016 Sep 9. EBioMedicine. 2016. PMID: 27633463 Free PMC article.
115 results