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G6PD activity contributes to the regulation of histone acetylation and gene expression in smooth muscle cells and to the pathogenesis of vascular diseases.
Dhagia V, Kitagawa A, Jacob C, Zheng C, D'Alessandro A, Edwards JG, Rocic P, Gupte R, Gupte SA. Dhagia V, et al. Among authors: kitagawa a. Am J Physiol Heart Circ Physiol. 2021 Mar 1;320(3):H999-H1016. doi: 10.1152/ajpheart.00488.2020. Epub 2021 Jan 8. Am J Physiol Heart Circ Physiol. 2021. PMID: 33416454 Free PMC article.
Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation.
Joshi SR, Kitagawa A, Jacob C, Hashimoto R, Dhagia V, Ramesh A, Zheng C, Zhang H, Jordan A, Waddell I, Leopold J, Hu CJ, McMurtry IF, D'Alessandro A, Stenmark KR, Gupte SA. Joshi SR, et al. Among authors: kitagawa a. Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1;318(4):L773-L786. doi: 10.1152/ajplung.00001.2020. Epub 2020 Mar 11. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32159369 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35553275
Global and endothelial G-protein coupled receptor 75 (GPR75) knockout relaxes pulmonary artery and mitigates hypoxia-induced pulmonary hypertension.
D'Addario CA, Matsumura S, Kitagawa A, Lainer GM, Zhang F, D'silva M, Khan MY, Froogh G, Gruzdev A, Zeldin DC, Schwartzman ML, Gupte SA. D'Addario CA, et al. Among authors: kitagawa a. Vascul Pharmacol. 2023 Dec;153:107235. doi: 10.1016/j.vph.2023.107235. Epub 2023 Sep 23. Vascul Pharmacol. 2023. PMID: 37742819
291 results