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Inhibitory signaling sustains a distinct early memory CD8+ T cell precursor that is resistant to DNA damage.
Johnnidis JB, Muroyama Y, Ngiow SF, Chen Z, Manne S, Cai Z, Song S, Platt JM, Schenkel JM, Abdel-Hakeem M, Beltra JC, Greenplate AR, Ali MA, Nzingha K, Giles JR, Harly C, Attanasio J, Pauken KE, Bengsch B, Paley MA, Tomov VT, Kurachi M, Vignali DAA, Sharpe AH, Reiner SL, Bhandoola A, Johnson FB, Wherry EJ. Johnnidis JB, et al. Among authors: pauken ke. Sci Immunol. 2021 Jan 15;6(55):eabe3702. doi: 10.1126/sciimmunol.abe3702. Sci Immunol. 2021. PMID: 33452106 Free PMC article.
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer.
Twyman-Saint Victor C, Rech AJ, Maity A, Rengan R, Pauken KE, Stelekati E, Benci JL, Xu B, Dada H, Odorizzi PM, Herati RS, Mansfield KD, Patsch D, Amaravadi RK, Schuchter LM, Ishwaran H, Mick R, Pryma DA, Xu X, Feldman MD, Gangadhar TC, Hahn SM, Wherry EJ, Vonderheide RH, Minn AJ. Twyman-Saint Victor C, et al. Among authors: pauken ke. Nature. 2015 Apr 16;520(7547):373-7. doi: 10.1038/nature14292. Epub 2015 Mar 9. Nature. 2015. PMID: 25754329 Free PMC article.
Overcoming T cell exhaustion in infection and cancer.
Pauken KE, Wherry EJ. Pauken KE, et al. Trends Immunol. 2015 Apr;36(4):265-76. doi: 10.1016/j.it.2015.02.008. Epub 2015 Mar 18. Trends Immunol. 2015. PMID: 25797516 Free PMC article. Review.
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells.
Gupta PK, Godec J, Wolski D, Adland E, Yates K, Pauken KE, Cosgrove C, Ledderose C, Junger WG, Robson SC, Wherry EJ, Alter G, Goulder PJ, Klenerman P, Sharpe AH, Lauer GM, Haining WN. Gupta PK, et al. Among authors: pauken ke. PLoS Pathog. 2015 Oct 20;11(10):e1005177. doi: 10.1371/journal.ppat.1005177. eCollection 2015 Oct. PLoS Pathog. 2015. PMID: 26485519 Free PMC article.
SnapShot: T Cell Exhaustion.
Pauken KE, Wherry EJ. Pauken KE, et al. Cell. 2015 Nov 5;163(4):1038-1038.e1. doi: 10.1016/j.cell.2015.10.054. Cell. 2015. PMID: 26544946 Free article. No abstract available.
CD4(+) T cell anergy prevents autoimmunity and generates regulatory T cell precursors.
Kalekar LA, Schmiel SE, Nandiwada SL, Lam WY, Barsness LO, Zhang N, Stritesky GL, Malhotra D, Pauken KE, Linehan JL, O'Sullivan MG, Fife BT, Hogquist KA, Jenkins MK, Mueller DL. Kalekar LA, et al. Among authors: pauken ke. Nat Immunol. 2016 Mar;17(3):304-14. doi: 10.1038/ni.3331. Epub 2016 Feb 1. Nat Immunol. 2016. PMID: 26829766 Free PMC article.
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