Choi HW - Search Results

1

E7766, a Macrocycle-Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan-Genotypic Activity.

Kim DS, Endo A, Fang FG, Huang KC, Bao X, Choi HW, Majumder U, Shen YY, Mathieu S, Zhu X, Sanders K, Noland T, Hao MH, Chen Y, Wang JY, Yasui S, TenDyke K, Wu J, Ingersoll C, Loiacono KA, Hutz JE, Sarwar N. Kim DS, et al. Among authors: choi hw. ChemMedChem. 2021 Jun 7;16(11):1740-1743. doi: 10.1002/cmdc.202100068. Epub 2021 Feb 25. ChemMedChem. 2021. PMID: 33522135

2

Apratoxin A Shows Novel Pancreas-Targeting Activity through the Binding of Sec 61.

Huang KC, Chen Z, Jiang Y, Akare S, Kolber-Simonds D, Condon K, Agoulnik S, Tendyke K, Shen Y, Wu KM, Mathieu S, Choi HW, Zhu X, Shimizu H, Kotake Y, Gerwick WH, Uenaka T, Woodall-Jappe M, Nomoto K. Huang KC, et al. Among authors: choi hw. Mol Cancer Ther. 2016 Jun;15(6):1208-16. doi: 10.1158/1535-7163.MCT-15-0648. Epub 2016 Mar 29. Mol Cancer Ther. 2016. PMID: 27196783

3

Synthesis of a Polycyclic Halichondrin C1-C14 Fragment via Intermolecular Oxy-Michael/ Trans-Ketalization.

Kim DS, Fang FG, Choi HW, Fang H. Kim DS, et al. Among authors: choi hw. J Org Chem. 2019 Apr 19;84(8):4898-4903. doi: 10.1021/acs.joc.8b02404. Epub 2018 Nov 15. J Org Chem. 2019. PMID: 30395467

4

Prins Reaction of Homoallenyl Alcohols: Access to Substituted Pyrans in the Halichondrin Series.

Choi HW, Fang FG, Fang H, Kim DS, Mathieu SR, Yu RT. Choi HW, et al. Org Lett. 2017 Nov 17;19(22):6092-6095. doi: 10.1021/acs.orglett.7b02934. Epub 2017 Oct 27. Org Lett. 2017. PMID: 29077412

5

Synthesis of the Halichondrin C1-C15 Fragment from a Halaven C27-C35 Byproduct: Stereospecific Intramolecular Kishi Reduction.

Kim DS, Fang FG, Choi HW, Fang H. Kim DS, et al. Among authors: choi hw. Org Lett. 2018 Jul 20;20(14):4295-4297. doi: 10.1021/acs.orglett.8b01715. Epub 2018 Jun 29. Org Lett. 2018. PMID: 29956939

6

Building C(sp³)-rich complexity by combining cycloaddition and C-C cross-coupling reactions.

Chen TG, Barton LM, Lin Y, Tsien J, Kossler D, Bastida I, Asai S, Bi C, Chen JS, Shan M, Fang H, Fang FG, Choi HW, Hawkins L, Qin T, Baran PS. Chen TG, et al. Among authors: choi hw. Nature. 2018 Aug;560(7718):350-354. doi: 10.1038/s41586-018-0391-9. Epub 2018 Jul 30. Nature. 2018. PMID: 30061620 Free PMC article.

7

EPZ011989, A Potent, Orally-Available EZH2 Inhibitor with Robust in Vivo Activity.

Campbell JE, Kuntz KW, Knutson SK, Warholic NM, Keilhack H, Wigle TJ, Raimondi A, Klaus CR, Rioux N, Yokoi A, Kawano S, Minoshima Y, Choi HW, Porter Scott M, Waters NJ, Smith JJ, Chesworth R, Moyer MP, Copeland RA. Campbell JE, et al. Among authors: choi hw. ACS Med Chem Lett. 2015 Mar 4;6(5):491-5. doi: 10.1021/acsmedchemlett.5b00037. eCollection 2015 May 14. ACS Med Chem Lett. 2015. PMID: 26005520 Free PMC article.

8

M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity against MET-Addicted Gastric Cancers.

Ohashi Y, Okamura M, Hirosawa A, Tamaki N, Akatsuka A, Wu KM, Choi HW, Yoshimatsu K, Shiina I, Yamori T, Dan S. Ohashi Y, et al. Among authors: choi hw. Cancer Res. 2016 Jul 1;76(13):3895-903. doi: 10.1158/0008-5472.CAN-15-2220. Epub 2016 Apr 12. Cancer Res. 2016. PMID: 27197184

9

Targeting the Golgi apparatus to overcome acquired resistance of non-small cell lung cancer cells to EGFR tyrosine kinase inhibitors.

Ohashi Y, Okamura M, Katayama R, Fang S, Tsutsui S, Akatsuka A, Shan M, Choi HW, Fujita N, Yoshimatsu K, Shiina I, Yamori T, Dan S. Ohashi Y, et al. Among authors: choi hw. Oncotarget. 2017 Dec 6;9(2):1641-1655. doi: 10.18632/oncotarget.22895. eCollection 2018 Jan 5. Oncotarget. 2017. PMID: 29416720 Free PMC article.

10

Plant-Entomopathogenic Fungi Interaction: Recent Progress and Future Prospects on Endophytism-Mediated Growth Promotion and Biocontrol.

Ahsan SM, Injamum-Ul-Hoque M, Das AK, Rahman MM, Mollah MMI, Paul NC, Choi HW. Ahsan SM, et al. Among authors: choi hw. Plants (Basel). 2024 May 20;13(10):1420. doi: 10.3390/plants13101420. Plants (Basel). 2024. PMID: 38794490 Free PMC article. Review.

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