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Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process.
Mimouni NEH, Paiva I, Barbotin AL, Timzoura FE, Plassard D, Le Gras S, Ternier G, Pigny P, Catteau-Jonard S, Simon V, Prevot V, Boutillier AL, Giacobini P. Mimouni NEH, et al. Among authors: le gras s. Cell Metab. 2021 Mar 2;33(3):513-530.e8. doi: 10.1016/j.cmet.2021.01.004. Epub 2021 Feb 3. Cell Metab. 2021. PMID: 33539777 Free PMC article.
Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator.
Chatterjee S, Cassel R, Schneider-Anthony A, Merienne K, Cosquer B, Tzeplaeff L, Halder Sinha S, Kumar M, Chaturbedy P, Eswaramoorthy M, Le Gras S, Keime C, Bousiges O, Dutar P, Petsophonsakul P, Rampon C, Cassel JC, Buée L, Blum D, Kundu TK, Boutillier AL. Chatterjee S, et al. Among authors: le gras s. EMBO Mol Med. 2018 Nov;10(11):e8587. doi: 10.15252/emmm.201708587. EMBO Mol Med. 2018. PMID: 30275019 Free PMC article.
Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription.
Paiva I, Cellai L, Meriaux C, Poncelet L, Nebie O, Saliou JM, Lacoste AS, Papegaey A, Drobecq H, Le Gras S, Schneider M, Malik EM, Müller CE, Faivre E, Carvalho K, Gomez-Murcia V, Vieau D, Thiroux B, Eddarkaoui S, Lebouvier T, Schueller E, Tzeplaeff L, Grgurina I, Seguin J, Stauber J, Lopes LV, Buée L, Buée-Scherrer V, Cunha RA, Ait-Belkacem R, Sergeant N, Annicotte JS, Boutillier AL, Blum D. Paiva I, et al. Among authors: le gras s. J Clin Invest. 2022 Jun 15;132(12):e149371. doi: 10.1172/JCI149371. J Clin Invest. 2022. PMID: 35536645 Free PMC article.
Polyglutamine-expanded ATXN7 alters a specific epigenetic signature underlying photoreceptor identity gene expression in SCA7 mouse retinopathy.
Niewiadomska-Cimicka A, Hache A, Le Gras S, Keime C, Ye T, Eisenmann A, Harichane I, Roux MJ, Messaddeq N, Clérin E, Léveillard T, Trottier Y. Niewiadomska-Cimicka A, et al. Among authors: le gras s. J Biomed Sci. 2022 Dec 20;29(1):107. doi: 10.1186/s12929-022-00892-1. J Biomed Sci. 2022. PMID: 36539812 Free PMC article.
Heterochromatin establishment during early mammalian development is regulated by pericentromeric RNA and characterized by non-repressive H3K9me3.
Burton A, Brochard V, Galan C, Ruiz-Morales ER, Rovira Q, Rodriguez-Terrones D, Kruse K, Le Gras S, Udayakumar VS, Chin HG, Eid A, Liu X, Wang C, Gao S, Pradhan S, Vaquerizas JM, Beaujean N, Jenuwein T, Torres-Padilla ME. Burton A, et al. Among authors: le gras s. Nat Cell Biol. 2020 Jul;22(7):767-778. doi: 10.1038/s41556-020-0536-6. Epub 2020 Jun 29. Nat Cell Biol. 2020. PMID: 32601371 Free PMC article.
TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway.
Rossitto M, Déjardin S, Rands CM, Le Gras S, Migale R, Rafiee MR, Neirijnck Y, Pruvost A, Nguyen AL, Bossis G, Cammas F, Le Gallic L, Wilhelm D, Lovell-Badge R, Boizet-Bonhoure B, Nef S, Poulat F. Rossitto M, et al. Among authors: le gras s. Nat Commun. 2022 Jul 29;13(1):4412. doi: 10.1038/s41467-022-32061-1. Nat Commun. 2022. PMID: 35906245 Free PMC article.
67 results