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The chaperone-binding activity of the mitochondrial surface receptor Tom70 protects the cytosol against mitoprotein-induced stress.
Backes S, Bykov YS, Flohr T, Räschle M, Zhou J, Lenhard S, Krämer L, Mühlhaus T, Bibi C, Jann C, Smith JD, Steinmetz LM, Rapaport D, Storchová Z, Schuldiner M, Boos F, Herrmann JM. Backes S, et al. Among authors: steinmetz lm. Cell Rep. 2021 Apr 6;35(1):108936. doi: 10.1016/j.celrep.2021.108936. Cell Rep. 2021. PMID: 33826901 Free PMC article.
Large scale microfluidic CRISPR screening for increased amylase secretion in yeast.
Johansson SA, Dulermo T, Jann C, Smith JD, Pryszlak A, Pignede G, Schraivogel D, Colavizza D, Desfougères T, Rave C, Farwick A, Merten CA, Roy KR, Wei W, Steinmetz LM. Johansson SA, et al. Among authors: steinmetz lm. Lab Chip. 2023 Aug 8;23(16):3704-3715. doi: 10.1039/d3lc00111c. Lab Chip. 2023. PMID: 37483015 Free PMC article.
Multiplexed precision genome editing with trackable genomic barcodes in yeast.
Roy KR, Smith JD, Vonesch SC, Lin G, Tu CS, Lederer AR, Chu A, Suresh S, Nguyen M, Horecka J, Tripathi A, Burnett WT, Morgan MA, Schulz J, Orsley KM, Wei W, Aiyar RS, Davis RW, Bankaitis VA, Haber JE, Salit ML, St Onge RP, Steinmetz LM. Roy KR, et al. Among authors: steinmetz lm. Nat Biotechnol. 2018 Jul;36(6):512-520. doi: 10.1038/nbt.4137. Epub 2018 May 7. Nat Biotechnol. 2018. PMID: 29734294 Free PMC article.
High-throughput functional characterization of protein phosphorylation sites in yeast.
Viéitez C, Busby BP, Ochoa D, Mateus A, Memon D, Galardini M, Yildiz U, Trovato M, Jawed A, Geiger AG, Oborská-Oplová M, Potel CM, Vonesch SC, Szu Tu C, Shahraz M, Stein F, Steinmetz LM, Panse VG, Noh KM, Savitski MM, Typas A, Beltrao P. Viéitez C, et al. Among authors: steinmetz lm. Nat Biotechnol. 2022 Mar;40(3):382-390. doi: 10.1038/s41587-021-01051-x. Epub 2021 Oct 18. Nat Biotechnol. 2022. PMID: 34663920 Free PMC article.
A genome-wide map of mitochondrial DNA recombination in yeast.
Fritsch ES, Chabbert CD, Klaus B, Steinmetz LM. Fritsch ES, et al. Among authors: steinmetz lm. Genetics. 2014 Oct;198(2):755-71. doi: 10.1534/genetics.114.166637. Epub 2014 Jul 31. Genetics. 2014. PMID: 25081569 Free PMC article.
Targeted Perturb-seq enables genome-scale genetic screens in single cells.
Schraivogel D, Gschwind AR, Milbank JH, Leonce DR, Jakob P, Mathur L, Korbel JO, Merten CA, Velten L, Steinmetz LM. Schraivogel D, et al. Among authors: steinmetz lm. Nat Methods. 2020 Jun;17(6):629-635. doi: 10.1038/s41592-020-0837-5. Epub 2020 Jun 1. Nat Methods. 2020. PMID: 32483332 Free PMC article.
218 results