CGP 48664, a new S-adenosylmethionine decarboxylase inhibitor with broad spectrum antiproliferative and antitumor activity.
Regenass U, Mett H, Stanek J, Mueller M, Kramer D, Porter CW.
Regenass U, et al. Among authors: stanek j.
Cancer Res. 1994 Jun 15;54(12):3210-7.
Cancer Res. 1994.
PMID: 8205541
From an ongoing effort to synthesize derivatives with increased enzyme specificity and potency and improved antitumor efficacy, we have now identified CGP 48664, a 4-amidinoindan-1-one 2'-amidinohydrazone (J. Stanek et al., J. Med. Chem., 36:2168-2171, 1993). …
From an ongoing effort to synthesize derivatives with increased enzyme specificity and potency and improved antitumor efficacy, we have now …