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A self-sustaining endocytic-based loop promotes breast cancer plasticity leading to aggressiveness and pro-metastatic behavior.
Schiano Lomoriello I, Giangreco G, Iavarone C, Tordonato C, Caldieri G, Serio G, Confalonieri S, Freddi S, Bianchi F, Pirroni S, Bertalot G, Viale G, Disalvatore D, Tosoni D, Malabarba MG, Disanza A, Scita G, Pece S, Pilcher BK, Vecchi M, Sigismund S, Di Fiore PP. Schiano Lomoriello I, et al. Among authors: sigismund s. Nat Commun. 2020 Jun 15;11(1):3020. doi: 10.1038/s41467-020-16836-y. Nat Commun. 2020. PMID: 32541686 Free PMC article.
EGFR Trafficking in Physiology and Cancer.
Caldieri G, Malabarba MG, Di Fiore PP, Sigismund S. Caldieri G, et al. Among authors: sigismund s. Prog Mol Subcell Biol. 2018;57:235-272. doi: 10.1007/978-3-319-96704-2_9. Prog Mol Subcell Biol. 2018. PMID: 30097778 Review.
Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling.
Pascolutti R, Algisi V, Conte A, Raimondi A, Pasham M, Upadhyayula S, Gaudin R, Maritzen T, Barbieri E, Caldieri G, Tordonato C, Confalonieri S, Freddi S, Malabarba MG, Maspero E, Polo S, Tacchetti C, Haucke V, Kirchhausen T, Di Fiore PP, Sigismund S. Pascolutti R, et al. Among authors: sigismund s. Cell Rep. 2019 Jun 4;27(10):3049-3061.e6. doi: 10.1016/j.celrep.2019.05.017. Cell Rep. 2019. PMID: 31167147 Free PMC article.
Reticulon 3-dependent ER-PM contact sites control EGFR nonclathrin endocytosis.
Caldieri G, Barbieri E, Nappo G, Raimondi A, Bonora M, Conte A, Verhoef LGGC, Confalonieri S, Malabarba MG, Bianchi F, Cuomo A, Bonaldi T, Martini E, Mazza D, Pinton P, Tacchetti C, Polo S, Di Fiore PP, Sigismund S. Caldieri G, et al. Among authors: sigismund s. Science. 2017 May 12;356(6338):617-624. doi: 10.1126/science.aah6152. Science. 2017. PMID: 28495747 Free PMC article.
Redundant and nonredundant organismal functions of EPS15 and EPS15L1.
Milesi C, Alberici P, Pozzi B, Oldani A, Beznoussenko GV, Raimondi A, Soppo BE, Amodio S, Caldieri G, Malabarba MG, Bertalot G, Confalonieri S, Parazzoli D, Mironov AA, Tacchetti C, Di Fiore PP, Sigismund S, Offenhäuser N. Milesi C, et al. Among authors: sigismund s. Life Sci Alliance. 2019 Jan 28;2(1):e201800273. doi: 10.26508/lsa.201800273. Print 2019 Feb. Life Sci Alliance. 2019. PMID: 30692166 Free PMC article.
Endocytic control of signaling at the plasma membrane.
Barbieri E, Di Fiore PP, Sigismund S. Barbieri E, et al. Among authors: sigismund s. Curr Opin Cell Biol. 2016 Apr;39:21-7. doi: 10.1016/j.ceb.2016.01.012. Epub 2016 Feb 10. Curr Opin Cell Biol. 2016. PMID: 26872272 Free article. Review.
PillarX: A Microfluidic Device to Profile Circulating Tumor Cell Clusters Based on Geometry, Deformability, and Epithelial State.
Green BJ, Marazzini M, Hershey B, Fardin A, Li Q, Wang Z, Giangreco G, Pisati F, Marchesi S, Disanza A, Frittoli E, Martini E, Magni S, Beznoussenko GV, Vernieri C, Lobefaro R, Parazzoli D, Maiuri P, Havas K, Labib M, Sigismund S, Fiore PPD, Gunby RH, Kelley SO, Scita G. Green BJ, et al. Among authors: sigismund s. Small. 2022 Apr;18(17):e2106097. doi: 10.1002/smll.202106097. Epub 2022 Mar 28. Small. 2022. PMID: 35344274 Free article.
45 results