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Liver homeostasis is maintained by midlobular zone 2 hepatocytes.
Wei Y, Wang YG, Jia Y, Li L, Yoon J, Zhang S, Wang Z, Zhang Y, Zhu M, Sharma T, Lin YH, Hsieh MH, Albrecht JH, Le PT, Rosen CJ, Wang T, Zhu H. Wei Y, et al. Among authors: wang yg, wang z, wang t. Science. 2021 Feb 26;371(6532):eabb1625. doi: 10.1126/science.abb1625. Science. 2021. PMID: 33632817 Free PMC article.
Somatic Mutations Increase Hepatic Clonal Fitness and Regeneration in Chronic Liver Disease.
Zhu M, Lu T, Jia Y, Luo X, Gopal P, Li L, Odewole M, Renteria V, Singal AG, Jang Y, Ge K, Wang SC, Sorouri M, Parekh JR, MacConmara MP, Yopp AC, Wang T, Zhu H. Zhu M, et al. Among authors: wang sc, wang t. Cell. 2019 Apr 18;177(3):608-621.e12. doi: 10.1016/j.cell.2019.03.026. Epub 2019 Apr 4. Cell. 2019. PMID: 30955891 Free PMC article.
Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury.
Lin YH, Zhang S, Zhu M, Lu T, Chen K, Wen Z, Wang S, Xiao G, Luo D, Jia Y, Li L, MacConmara M, Hoshida Y, Singal AG, Yopp A, Wang T, Zhu H. Lin YH, et al. Among authors: wang t, wang s. Gastroenterology. 2020 May;158(6):1698-1712.e14. doi: 10.1053/j.gastro.2020.01.026. Epub 2020 Jan 20. Gastroenterology. 2020. PMID: 31972235 Free PMC article.
LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.
Choi JH, Zhong X, McAlpine W, Liao TC, Zhang D, Fang B, Russell J, Ludwig S, Nair-Gill E, Zhang Z, Wang KW, Misawa T, Zhan X, Choi M, Wang T, Li X, Tang M, Sun Q, Yu L, Murray AR, Moresco EMY, Beutler B. Choi JH, et al. Among authors: wang kw, wang t. Science. 2019 May 10;364(6440):eaau0812. doi: 10.1126/science.aau0812. Science. 2019. PMID: 31073040 Free PMC article.
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