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Mapping of Genomic Vulnerabilities in the Post-Translational Ubiquitination, SUMOylation and Neddylation Machinery in Breast Cancer.
Fuentes-Antrás J, Alcaraz-Sanabria AL, Morafraile EC, Noblejas-López MDM, Galán-Moya EM, Baliu-Pique M, López-Cade I, García-Barberán V, Pérez-Segura P, Manzano A, Pandiella A, Győrffy B, Ocaña A. Fuentes-Antrás J, et al. Among authors: morafraile ec. Cancers (Basel). 2021 Feb 17;13(4):833. doi: 10.3390/cancers13040833. Cancers (Basel). 2021. PMID: 33671201 Free PMC article.
Clinical considerations for the design of PROTACs in cancer.
Nieto-Jiménez C, Morafraile EC, Alonso-Moreno C, Ocaña A. Nieto-Jiménez C, et al. Among authors: morafraile ec. Mol Cancer. 2022 Mar 7;21(1):67. doi: 10.1186/s12943-022-01535-7. Mol Cancer. 2022. PMID: 35249548 Free PMC article. Review.
Checkpoint inhibition of origin firing prevents DNA topological stress.
Morafraile EC, Hänni C, Allen G, Zeisner T, Clarke C, Johnson MC, Santos MM, Carroll L, Minchell NE, Baxter J, Banks P, Lydall D, Zegerman P. Morafraile EC, et al. Genes Dev. 2019 Nov 1;33(21-22):1539-1554. doi: 10.1101/gad.328682.119. Epub 2019 Oct 17. Genes Dev. 2019. PMID: 31624083 Free PMC article.