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Investigation of the pathways related to intrinsic miltefosine tolerance in Leishmania (Viannia) braziliensis clinical isolates reveals differences in drug uptake.
Espada CR, Magalhães RM, Cruz MC, Machado PR, Schriefer A, Carvalho EM, Hornillos V, Alves JM, Cruz AK, Coelho AC, Uliana SRB. Espada CR, et al. Among authors: hornillos v. Int J Parasitol Drugs Drug Resist. 2019 Dec;11:139-147. doi: 10.1016/j.ijpddr.2019.02.005. Epub 2019 Feb 25. Int J Parasitol Drugs Drug Resist. 2019. PMID: 30850347 Free PMC article.
Defeating Leishmania resistance to miltefosine (hexadecylphosphocholine) by peptide-mediated drug smuggling: a proof of mechanism for trypanosomatid chemotherapy.
Luque-Ortega JR, de la Torre BG, Hornillos V, Bart JM, Rueda C, Navarro M, Amat-Guerri F, Acuña AU, Andreu D, Rivas L. Luque-Ortega JR, et al. Among authors: hornillos v. J Control Release. 2012 Aug 10;161(3):835-42. doi: 10.1016/j.jconrel.2012.05.023. Epub 2012 May 18. J Control Release. 2012. PMID: 22609351
Involvement of lipid rafts in the localization and dysfunction effect of the antitumor ether phospholipid edelfosine in mitochondria.
Mollinedo F, Fernández M, Hornillos V, Delgado J, Amat-Guerri F, Acuña AU, Nieto-Miguel T, Villa-Pulgarín JA, González-García C, Ceña V, Gajate C. Mollinedo F, et al. Among authors: hornillos v. Cell Death Dis. 2011 May 19;2(5):e158. doi: 10.1038/cddis.2011.41. Cell Death Dis. 2011. PMID: 21593790 Free PMC article.
44 results