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Interfering with Metabolic Profile of Triple-Negative Breast Cancers Using Rationally Designed Metformin Prodrugs.
Babak MV, Chong KR, Rapta P, Zannikou M, Tang HM, Reichert L, Chang MR, Kushnarev V, Heffeter P, Meier-Menches SM, Lim ZC, Yap JY, Casini A, Balyasnikova IV, Ang WH. Babak MV, et al. Among authors: heffeter p. Angew Chem Int Ed Engl. 2021 Jun 7;60(24):13405-13413. doi: 10.1002/anie.202102266. Epub 2021 May 6. Angew Chem Int Ed Engl. 2021. PMID: 33755286
Synthesis and Preclinical Evaluation of Radiolabeled [103Ru]BOLD-100.
Happl B, Brandt M, Balber T, Benčurová K, Talip Z, Voegele A, Heffeter P, Kandioller W, Van der Meulen NP, Mitterhauser M, Hacker M, Keppler BK, Mindt TL. Happl B, et al. Among authors: heffeter p. Pharmaceutics. 2023 Nov 15;15(11):2626. doi: 10.3390/pharmaceutics15112626. Pharmaceutics. 2023. PMID: 38004604 Free PMC article.
Tumor-targeting of EGFR inhibitors by hypoxia-mediated activation.
Karnthaler-Benbakka C, Groza D, Kryeziu K, Pichler V, Roller A, Berger W, Heffeter P, Kowol CR. Karnthaler-Benbakka C, et al. Among authors: heffeter p. Angew Chem Int Ed Engl. 2014 Nov 17;53(47):12930-12935. doi: 10.1002/anie.201403936. Epub 2014 Jul 30. Angew Chem Int Ed Engl. 2014. PMID: 25079700 Free PMC article.
Lipid droplet-mediated scavenging as novel intrinsic and adaptive resistance factor against the multikinase inhibitor ponatinib.
Englinger B, Laemmerer A, Moser P, Kallus S, Röhrl C, Pirker C, Baier D, Mohr T, Niederstaetter L, Meier-Menches SM, Gerner C, Gabler L, Gojo J, Timelthaler G, Senkiv J, Jäger W, Kowol CR, Heffeter P, Berger W. Englinger B, et al. Among authors: heffeter p. Int J Cancer. 2020 Sep 15;147(6):1680-1693. doi: 10.1002/ijc.32924. Epub 2020 Mar 2. Int J Cancer. 2020. PMID: 32064608 Free PMC article.
Structure-Activity Relationships of Triple-Action Platinum(IV) Prodrugs with Albumin-Binding Properties and Immunomodulating Ligands.
Fronik P, Poetsch I, Kastner A, Mendrina T, Hager S, Hohenwallner K, Schueffl H, Herndler-Brandstetter D, Koellensperger G, Rampler E, Kopecka J, Riganti C, Berger W, Keppler BK, Heffeter P, Kowol CR. Fronik P, et al. Among authors: heffeter p. J Med Chem. 2021 Aug 26;64(16):12132-12151. doi: 10.1021/acs.jmedchem.1c00770. Epub 2021 Aug 17. J Med Chem. 2021. PMID: 34403254 Free PMC article.
161 results