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Inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and attenuates atherosclerosis and obesity in mice.
Voisin M, Shrestha E, Rollet C, Nikain CA, Josefs T, Mahé M, Barrett TJ, Chang HR, Ruoff R, Schneider JA, Garabedian ML, Zoumadakis C, Yun C, Badwan B, Brown EJ, Mar AC, Schneider RJ, Goldberg IJ, Pineda-Torra I, Fisher EA, Garabedian MJ. Voisin M, et al. Among authors: fisher ea. Commun Biol. 2021 Mar 26;4(1):420. doi: 10.1038/s42003-021-01925-5. Commun Biol. 2021. PMID: 33772096 Free PMC article.
LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression.
Feig JE, Pineda-Torra I, Sanson M, Bradley MN, Vengrenyuk Y, Bogunovic D, Gautier EL, Rubinstein D, Hong C, Liu J, Wu C, van Rooijen N, Bhardwaj N, Garabedian M, Tontonoz P, Fisher EA. Feig JE, et al. Among authors: fisher ea. J Clin Invest. 2010 Dec;120(12):4415-24. doi: 10.1172/JCI38911. J Clin Invest. 2010. PMID: 21041949 Free PMC article.
Hyperglycemia promotes myelopoiesis and impairs the resolution of atherosclerosis.
Nagareddy PR, Murphy AJ, Stirzaker RA, Hu Y, Yu S, Miller RG, Ramkhelawon B, Distel E, Westerterp M, Huang LS, Schmidt AM, Orchard TJ, Fisher EA, Tall AR, Goldberg IJ. Nagareddy PR, et al. Among authors: fisher ea. Cell Metab. 2013 May 7;17(5):695-708. doi: 10.1016/j.cmet.2013.04.001. Cell Metab. 2013. PMID: 23663738 Free PMC article.
458 results