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MPV17 Mutations Are Associated With a Quiescent Energetic Metabolic Profile.
Jacinto S, Guerreiro P, de Oliveira RM, Cunha-Oliveira T, Santos MJ, Grazina M, Rego AC, Outeiro TF. Jacinto S, et al. Among authors: outeiro tf. Front Cell Neurosci. 2021 Mar 17;15:641264. doi: 10.3389/fncel.2021.641264. eCollection 2021. Front Cell Neurosci. 2021. PMID: 33815063 Free PMC article.
Sirtuins: common targets in aging and in neurodegeneration.
de Oliveira RM, Pais TF, Outeiro TF. de Oliveira RM, et al. Among authors: outeiro tf. Curr Drug Targets. 2010 Oct;11(10):1270-80. doi: 10.2174/1389450111007011270. Curr Drug Targets. 2010. PMID: 20840069 Review.
Impaired proteostasis contributes to renal tubular dysgenesis.
de Oliveira RM, Marijanovic Z, Carvalho F, Miltényi GM, Matos JE, Tenreiro S, Oliveira S, Enguita FJ, Stone R, Outeiro TF. de Oliveira RM, et al. Among authors: outeiro tf. PLoS One. 2011;6(6):e20854. doi: 10.1371/journal.pone.0020854. Epub 2011 Jun 9. PLoS One. 2011. PMID: 21695262 Free PMC article.
SIRT2 as a Therapeutic Target for Age-Related Disorders.
de Oliveira RM, Sarkander J, Kazantsev AG, Outeiro TF. de Oliveira RM, et al. Among authors: outeiro tf. Front Pharmacol. 2012 May 3;3:82. doi: 10.3389/fphar.2012.00082. eCollection 2012. Front Pharmacol. 2012. PMID: 22563317 Free PMC article.
Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation.
Diógenes MJ, Dias RB, Rombo DM, Vicente Miranda H, Maiolino F, Guerreiro P, Näsström T, Franquelim HG, Oliveira LM, Castanho MA, Lannfelt L, Bergström J, Ingelsson M, Quintas A, Sebastião AM, Lopes LV, Outeiro TF. Diógenes MJ, et al. Among authors: outeiro tf. J Neurosci. 2012 Aug 22;32(34):11750-62. doi: 10.1523/JNEUROSCI.0234-12.2012. J Neurosci. 2012. PMID: 22915117 Free PMC article.
α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner.
Yin G, Lopes da Fonseca T, Eisbach SE, Anduaga AM, Breda C, Orcellet ML, Szegő ÉM, Guerreiro P, Lázaro DF, Braus GH, Fernandez CO, Griesinger C, Becker S, Goody RS, Itzen A, Giorgini F, Outeiro TF, Zweckstetter M. Yin G, et al. Among authors: outeiro tf. Neurobiol Dis. 2014 Oct;70:149-61. doi: 10.1016/j.nbd.2014.06.018. Epub 2014 Jun 28. Neurobiol Dis. 2014. PMID: 24983211
The small GTPase Rab11 co-localizes with α-synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity.
Chutna O, Gonçalves S, Villar-Piqué A, Guerreiro P, Marijanovic Z, Mendes T, Ramalho J, Emmanouilidou E, Ventura S, Klucken J, Barral DC, Giorgini F, Vekrellis K, Outeiro TF. Chutna O, et al. Among authors: outeiro tf. Hum Mol Genet. 2014 Dec 20;23(25):6732-45. doi: 10.1093/hmg/ddu391. Epub 2014 Aug 4. Hum Mol Genet. 2014. PMID: 25092884
329 results