Kool J - Search Results

1

Erythrocyte haemotoxicity profiling of snake venom toxins after nanofractionation.

Xie C, Bittenbinder MA, Slagboom J, Arrahman A, Bruijns S, Somsen GW, Vonk FJ, Casewell NR, García-Vallejo JJ, Kool J. Xie C, et al. Among authors: kool j. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Jun 30;1176:122586. doi: 10.1016/j.jchromb.2021.122586. Epub 2021 Feb 16. J Chromatogr B Analyt Technol Biomed Life Sci. 2021. PMID: 33839052 Free PMC article.

2

Cytochrome P450 bio-affinity detection coupled to gradient HPLC: on-line screening of affinities to cytochrome P4501A2 and 2D6.

Kool J, van Liempd SM, Harmsen S, Beckman J, van Elswijk D, Commandeur JN, Irth H, Vermeulen NP. Kool J, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Oct 15;858(1-2):49-58. doi: 10.1016/j.jchromb.2007.08.005. Epub 2007 Aug 17. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17826363

3

Microfractionation revisited: a 1536 well high resolution screening assay.

Giera M, Heus F, Janssen L, Kool J, Lingeman H, Irth H. Giera M, et al. Among authors: kool j. Anal Chem. 2009 Jul 1;81(13):5460-6. doi: 10.1021/ac900622b. Anal Chem. 2009. PMID: 19507859

4

Development of an on-line weak-cation exchange liquid chromatography-tandem mass spectrometric method for screening aldehyde products in biological matrices.

Eggink M, Charret S, Wijtmans M, Lingeman H, Kool J, Niessen WM, Irth H. Eggink M, et al. Among authors: kool j. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Dec 1;877(31):3937-45. doi: 10.1016/j.jchromb.2009.09.043. Epub 2009 Oct 14. J Chromatogr B Analyt Technol Biomed Life Sci. 2009. PMID: 19880357

5

Determination and identification of estrogenic compounds generated with biosynthetic enzymes using hyphenated screening assays, high resolution mass spectrometry and off-line NMR.

de Vlieger JS, Kolkman AJ, Ampt KA, Commandeur JN, Vermeulen NP, Kool J, Wijmenga SS, Niessen WM, Irth H, Honing M. de Vlieger JS, et al. Among authors: kool j. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Mar 1;878(7-8):667-74. doi: 10.1016/j.jchromb.2010.01.035. Epub 2010 Jan 29. J Chromatogr B Analyt Technol Biomed Life Sci. 2010. PMID: 20149764

6

Nanofractionation spotter technology for rapid contactless and high-resolution deposition of LC eluent for further off-line analysis.

Kool J, de Kloe G, Denker AD, van Altena K, Smoluch M, van Iperen D, Nahar TT, Limburg RJ, Niessen WM, Lingeman H, Leurs R, de Esch IJ, Smit AB, Irth H. Kool J, et al. Anal Chem. 2011 Jan 1;83(1):125-32. doi: 10.1021/ac102001g. Epub 2010 Nov 30. Anal Chem. 2011. PMID: 21117623

7

Online magnetic bead based dynamic protein affinity selection coupled to LC-MS for the screening of acetylcholine binding protein ligands.

Pochet L, Heus F, Jonker N, Lingeman H, Smit AB, Niessen WM, Kool J. Pochet L, et al. Among authors: kool j. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jun 15;879(20):1781-8. doi: 10.1016/j.jchromb.2011.04.023. Epub 2011 Apr 28. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21565564

8

High-resolution bioactivity profiling of mixtures toward the acetylcholine binding protein using a nanofractionation spotter technology.

Kool J, Heus F, de Kloe G, Lingeman H, Smit AB, Leurs R, Edink E, De Esch IJ, Irth H, Niessen WM. Kool J, et al. J Biomol Screen. 2011 Sep;16(8):917-24. doi: 10.1177/1087057111413921. Epub 2011 Jul 28. J Biomol Screen. 2011. PMID: 21799121

9

High-resolution metabolic profiling towards G protein-coupled receptors: rapid and comprehensive screening of histamine H₄ receptor ligands.

Kool J, Rudebeck AF, Fleurbaaij F, Nijmeijer S, Falck D, Smits RA, Vischer HF, Leurs R, Niessen WM. Kool J, et al. J Chromatogr A. 2012 Oct 12;1259:213-20. doi: 10.1016/j.chroma.2012.03.052. Epub 2012 Mar 22. J Chromatogr A. 2012. PMID: 22520160

10

Development of a profiling strategy for metabolic mixtures by combining chromatography and mass spectrometry with cell-based GPCR signaling.

Nijmeijer S, Vischer HF, Rudebeck AF, Fleurbaaij F, Falck D, Leurs R, Niessen WM, Kool J. Nijmeijer S, et al. Among authors: kool j. J Biomol Screen. 2012 Dec;17(10):1329-38. doi: 10.1177/1087057112451922. Epub 2012 Jun 26. J Biomol Screen. 2012. PMID: 22740245

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