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Clonal multi-omics reveals Bcor as a negative regulator of emergency dendritic cell development.
Tian L, Tomei S, Schreuder J, Weber TS, Amann-Zalcenstein D, Lin DS, Tran J, Audiger C, Chu M, Jarratt A, Willson T, Hilton A, Pang ES, Patton T, Kelly M, Su S, Gouil Q, Diakumis P, Bahlo M, Sargeant T, Kats LM, Hodgkin PD, O'Keeffe M, Ng AP, Ritchie ME, Naik SH. Tian L, et al. Among authors: jarratt a. Immunity. 2021 Jun 8;54(6):1338-1351.e9. doi: 10.1016/j.immuni.2021.03.012. Epub 2021 Apr 15. Immunity. 2021. PMID: 33862015 Free article.
A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics.
Amann-Zalcenstein D, Tian L, Schreuder J, Tomei S, Lin DS, Fairfax KA, Bolden JE, McKenzie MD, Jarratt A, Hilton A, Jackson JT, Di Rago L, McCormack MP, de Graaf CA, Stonehouse O, Taoudi S, Alexander WS, Nutt SL, Ritchie ME, Ng AP, Naik SH. Amann-Zalcenstein D, et al. Among authors: jarratt a. Nat Immunol. 2020 Dec;21(12):1574-1584. doi: 10.1038/s41590-020-0799-x. Epub 2020 Oct 19. Nat Immunol. 2020. PMID: 33077975
Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy.
Thijssen R, Tian L, Anderson MA, Flensburg C, Jarratt A, Garnham AL, Jabbari JS, Peng H, Lew TE, Teh CE, Gouil Q, Georgiou A, Tan T, Djajawi TM, Tam CS, Seymour JF, Blombery P, Gray DHD, Majewski IJ, Ritchie ME, Roberts AW, Huang DCS. Thijssen R, et al. Among authors: jarratt a. Blood. 2022 Nov 17;140(20):2127-2141. doi: 10.1182/blood.2022016040. Blood. 2022. PMID: 35709339 Free PMC article.
BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation.
Keniry A, Jansz N, Gearing LJ, Wanigasuriya I, Chen J, Nefzger CM, Hickey PF, Gouil Q, Liu J, Breslin KA, Iminitoff M, Beck T, Tapia Del Fierro A, Whitehead L, Jarratt A, Kinkel SA, Taberlay PC, Willson T, Pakusch M, Ritchie ME, Hilton DJ, Polo JM, Blewitt ME. Keniry A, et al. Among authors: jarratt a. Nat Commun. 2022 Mar 29;13(1):1658. doi: 10.1038/s41467-022-29333-1. Nat Commun. 2022. PMID: 35351876 Free PMC article.
An experimentally validated network of nine haematopoietic transcription factors reveals mechanisms of cell state stability.
Schütte J, Wang H, Antoniou S, Jarratt A, Wilson NK, Riepsaame J, Calero-Nieto FJ, Moignard V, Basilico S, Kinston SJ, Hannah RL, Chan MC, Nürnberg ST, Ouwehand WH, Bonzanni N, de Bruijn MF, Göttgens B. Schütte J, et al. Among authors: jarratt a. Elife. 2016 Feb 22;5:e11469. doi: 10.7554/eLife.11469. Elife. 2016. PMID: 26901438 Free PMC article.
Alternative Runx1 promoter usage in mouse developmental hematopoiesis.
Bee T, Liddiard K, Swiers G, Bickley SR, Vink CS, Jarratt A, Hughes JR, Medvinsky A, de Bruijn MF. Bee T, et al. Among authors: jarratt a. Blood Cells Mol Dis. 2009 Jul-Aug;43(1):35-42. doi: 10.1016/j.bcmd.2009.03.011. Epub 2009 May 21. Blood Cells Mol Dis. 2009. PMID: 19464215
Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes.
Zhou X, Feliciano P, Shu C, Wang T, Astrovskaya I, Hall JB, Obiajulu JU, Wright JR, Murali SC, Xu SX, Brueggeman L, Thomas TR, Marchenko O, Fleisch C, Barns SD, Snyder LG, Han B, Chang TS, Turner TN, Harvey WT, Nishida A, O'Roak BJ, Geschwind DH; SPARK Consortium; Michaelson JJ, Volfovsky N, Eichler EE, Shen Y, Chung WK. Zhou X, et al. Nat Genet. 2022 Sep;54(9):1305-1319. doi: 10.1038/s41588-022-01148-2. Epub 2022 Aug 18. Nat Genet. 2022. PMID: 35982159 Free PMC article.
12 results