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SARS-CoV-2 B.1.1.7 and B.1.351 variants of concern induce lethal disease in K18-hACE2 transgenic mice despite convalescent plasma therapy.
Horspool AM, Ye C, Wong TY, Russ BP, Lee KS, Winters MT, Bevere JR, Kieffer T, Martinez I, Sourimant J, Greninger A, Plemper RK, Denvir J, Cyphert HA, Torrelles J, Martinez-Sobrido L, Damron FH. Horspool AM, et al. Among authors: greninger a. bioRxiv [Preprint]. 2021 May 5:2021.05.05.442784. doi: 10.1101/2021.05.05.442784. bioRxiv. 2021. PMID: 33972945 Free PMC article. Preprint.
A Bifluorescent-Based Assay for the Identification of Neutralizing Antibodies against SARS-CoV-2 Variants of Concern In Vitro and In Vivo.
Chiem K, Morales Vasquez D, Silvas JA, Park JG, Piepenbrink MS, Sourimant J, Lin MJ, Greninger AL, Plemper RK, Torrelles JB, Walter MR, de la Torre JC, Kobie JK, Ye C, Martinez-Sobrido L. Chiem K, et al. Among authors: greninger al. J Virol. 2021 Oct 27;95(22):e0112621. doi: 10.1128/JVI.01126-21. Epub 2021 Sep 8. J Virol. 2021. PMID: 34495697 Free PMC article.
Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses.
Ye C, Chiem K, Park JG, Silvas JA, Morales Vasquez D, Sourimant J, Lin MJ, Greninger AL, Plemper RK, Torrelles JB, Kobie JJ, Walter MR, de la Torre JC, Martinez-Sobrido L. Ye C, et al. Among authors: greninger al. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2111593118. doi: 10.1073/pnas.2111593118. Proc Natl Acad Sci U S A. 2021. PMID: 34561300 Free PMC article.
Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets.
Cox RM, Wolf JD, Lieber CM, Sourimant J, Lin MJ, Babusis D, DuPont V, Chan J, Barrett KT, Lye D, Kalla R, Chun K, Mackman RL, Ye C, Cihlar T, Martinez-Sobrido L, Greninger AL, Bilello JP, Plemper RK. Cox RM, et al. Nat Commun. 2021 Nov 5;12(1):6415. doi: 10.1038/s41467-021-26760-4. Nat Commun. 2021. PMID: 34741049 Free PMC article.
Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice.
Wong TY, Horspool AM, Russ BP, Ye C, Lee KS, Winters MT, Bevere JR, Miller OA, Rader NA, Cooper M, Kieffer T, Sourimant J, Greninger AL, Plemper RK, Denvir J, Cyphert HA, Barbier M, Torrelles JB, Martinez I, Martinez-Sobrido L, Damron FH. Wong TY, et al. Among authors: greninger al. J Virol. 2022 Mar 23;96(6):e0218421. doi: 10.1128/jvi.02184-21. Epub 2022 Jan 26. J Virol. 2022. PMID: 35080423 Free PMC article.
Paxlovid-like nirmatrelvir/ritonavir fails to block SARS-CoV-2 transmission in ferrets.
Cox RM, Lieber CM, Wolf JD, Karimi A, Lieberman NAP, Sticher ZM, Roychoudhury P, Andrews MK, Krueger RE, Natchus MG, Painter GR, Kolykhalov AA, Greninger AL, Plemper RK. Cox RM, et al. Among authors: greninger al. bioRxiv [Preprint]. 2022 Nov 21:2022.11.20.517271. doi: 10.1101/2022.11.20.517271. bioRxiv. 2022. PMID: 36451893 Free PMC article. Preprint.
379 results