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CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory.
Lelliott EJ, Kong IY, Zethoven M, Ramsbottom KM, Martelotto LG, Meyran D, Zhu JJ, Costacurta M, Kirby L, Sandow JJ, Lim L, Dominguez PM, Todorovski I, Haynes NM, Beavis PA, Neeson PJ, Hawkins ED, McArthur GA, Parish IA, Johnstone RW, Oliaro J, Sheppard KE, Kearney CJ, Vervoort SJ. Lelliott EJ, et al. Among authors: ramsbottom km. Cancer Discov. 2021 Oct;11(10):2582-2601. doi: 10.1158/2159-8290.CD-20-1554. Epub 2021 May 14. Cancer Discov. 2021. PMID: 33990344
Antagonism of IAPs Enhances CAR T-cell Efficacy.
Michie J, Beavis PA, Freeman AJ, Vervoort SJ, Ramsbottom KM, Narasimhan V, Lelliott EJ, Lalaoui N, Ramsay RG, Johnstone RW, Silke J, Darcy PK, Voskoboinik I, Kearney CJ, Oliaro J. Michie J, et al. Among authors: ramsbottom km. Cancer Immunol Res. 2019 Feb;7(2):183-192. doi: 10.1158/2326-6066.CIR-18-0428. Epub 2019 Jan 16. Cancer Immunol Res. 2019. PMID: 30651288
Combined BRAF, MEK, and CDK4/6 Inhibition Depletes Intratumoral Immune-Potentiating Myeloid Populations in Melanoma.
Lelliott EJ, Mangiola S, Ramsbottom KM, Zethoven M, Lim L, Lau PKH, Oliver AJ, Martelotto LG, Kirby L, Martin C, Patel RP, Slater A, Cullinane C, Papenfuss AT, Haynes NM, McArthur GA, Oliaro J, Sheppard KE. Lelliott EJ, et al. Among authors: ramsbottom km. Cancer Immunol Res. 2021 Feb;9(2):136-146. doi: 10.1158/2326-6066.CIR-20-0401. Epub 2020 Dec 10. Cancer Immunol Res. 2021. PMID: 33303574
BET Inhibition Enhances TNF-Mediated Antitumor Immunity.
Wellinger LC, Hogg SJ, Newman DM, Friess T, Geiss D, Michie J, Ramsbottom KM, Bacac M, Fauti T, Marbach D, Jarassier L, Thienger P, Paehler A, Cluse LA, Kearney CJ, Vervoort SJ, Trapani JA, Oliaro J, Shortt J, Ruefli-Brasse A, Rohle D, Johnstone RW. Wellinger LC, et al. Among authors: ramsbottom km. Cancer Immunol Res. 2022 Jan;10(1):87-107. doi: 10.1158/2326-6066.CIR-21-0224. Epub 2021 Nov 15. Cancer Immunol Res. 2022. PMID: 34782346
SUGAR-seq enables simultaneous detection of glycans, epitopes, and the transcriptome in single cells.
Kearney CJ, Vervoort SJ, Ramsbottom KM, Todorovski I, Lelliott EJ, Zethoven M, Pijpers L, Martin BP, Semple T, Martelotto L, Trapani JA, Parish IA, Scott NE, Oliaro J, Johnstone RW. Kearney CJ, et al. Among authors: ramsbottom km. Sci Adv. 2021 Feb 19;7(8):eabe3610. doi: 10.1126/sciadv.abe3610. Print 2021 Feb. Sci Adv. 2021. PMID: 33608275 Free PMC article.
A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapy.
Lelliott EJ, Cullinane C, Martin CA, Walker R, Ramsbottom KM, Souza-Fonseca-Guimaraes F, Abuhammad S, Michie J, Kirby L, Young RJ, Slater A, Lau P, Meeth K, Oliaro J, Haynes N, McArthur GA, Sheppard KE. Lelliott EJ, et al. Among authors: ramsbottom km. Sci Rep. 2019 Feb 4;9(1):1225. doi: 10.1038/s41598-018-37883-y. Sci Rep. 2019. PMID: 30718660 Free PMC article.
Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion.
Freeman AJ, Vervoort SJ, Ramsbottom KM, Kelly MJ, Michie J, Pijpers L, Johnstone RW, Kearney CJ, Oliaro J. Freeman AJ, et al. Among authors: ramsbottom km. Cell Rep. 2019 Sep 10;28(11):2784-2794.e5. doi: 10.1016/j.celrep.2019.08.017. Cell Rep. 2019. PMID: 31509742 Free article.
25 results