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m6A RNA methylation of major satellite repeat transcripts facilitates chromatin association and RNA:DNA hybrid formation in mouse heterochromatin.
Duda KJ, Ching RW, Jerabek L, Shukeir N, Erikson G, Engist B, Onishi-Seebacher M, Perrera V, Richter F, Mittler G, Fritz K, Helm M, Knuckles P, Bühler M, Jenuwein T. Duda KJ, et al. Among authors: helm m. Nucleic Acids Res. 2021 Jun 4;49(10):5568-5587. doi: 10.1093/nar/gkab364. Nucleic Acids Res. 2021. PMID: 33999208 Free PMC article.
The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent.
Hauenschild R, Tserovski L, Schmid K, Thüring K, Winz ML, Sharma S, Entian KD, Wacheul L, Lafontaine DL, Anderson J, Alfonzo J, Hildebrandt A, Jäschke A, Motorin Y, Helm M. Hauenschild R, et al. Among authors: helm m. Nucleic Acids Res. 2015 Nov 16;43(20):9950-64. doi: 10.1093/nar/gkv895. Epub 2015 Sep 13. Nucleic Acids Res. 2015. PMID: 26365242 Free PMC article.
Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine.
Müller M, Hartmann M, Schuster I, Bender S, Thüring KL, Helm M, Katze JR, Nellen W, Lyko F, Ehrenhofer-Murray AE. Müller M, et al. Among authors: helm m. Nucleic Acids Res. 2015 Dec 15;43(22):10952-62. doi: 10.1093/nar/gkv980. Epub 2015 Sep 30. Nucleic Acids Res. 2015. PMID: 26424849 Free PMC article.
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d.
Knuckles P, Lence T, Haussmann IU, Jacob D, Kreim N, Carl SH, Masiello I, Hares T, Villaseñor R, Hess D, Andrade-Navarro MA, Biggiogera M, Helm M, Soller M, Bühler M, Roignant JY. Knuckles P, et al. Among authors: helm m. Genes Dev. 2018 Mar 1;32(5-6):415-429. doi: 10.1101/gad.309146.117. Epub 2018 Mar 13. Genes Dev. 2018. PMID: 29535189 Free PMC article.
Machine learning of reverse transcription signatures of variegated polymerases allows mapping and discrimination of methylated purines in limited transcriptomes.
Werner S, Schmidt L, Marchand V, Kemmer T, Falschlunger C, Sednev MV, Bec G, Ennifar E, Höbartner C, Micura R, Motorin Y, Hildebrandt A, Helm M. Werner S, et al. Among authors: helm m. Nucleic Acids Res. 2020 Apr 17;48(7):3734-3746. doi: 10.1093/nar/gkaa113. Nucleic Acids Res. 2020. PMID: 32095818 Free PMC article.
Hakai is required for stabilization of core components of the m6A mRNA methylation machinery.
Bawankar P, Lence T, Paolantoni C, Haussmann IU, Kazlauskiene M, Jacob D, Heidelberger JB, Richter FM, Nallasivan MP, Morin V, Kreim N, Beli P, Helm M, Jinek M, Soller M, Roignant JY. Bawankar P, et al. Among authors: helm m. Nat Commun. 2021 Jun 18;12(1):3778. doi: 10.1038/s41467-021-23892-5. Nat Commun. 2021. PMID: 34145251 Free PMC article.
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