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ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity.
Shum M, Shintre CA, Althoff T, Gutierrez V, Segawa M, Saxberg AD, Martinez M, Adamson R, Young MR, Faust B, Gharakhanian R, Su S, Chella Krishnan K, Mahdaviani K, Veliova M, Wolf DM, Ngo J, Nocito L, Stiles L, Abramson J, Lusis AJ, Hevener AL, Zoghbi ME, Carpenter EP, Liesa M. Shum M, et al. Among authors: carpenter ep. Sci Transl Med. 2021 May 19;13(594):eabd1869. doi: 10.1126/scitranslmed.abd1869. Sci Transl Med. 2021. PMID: 34011630 Free PMC article.
Structures and functions of mitochondrial ABC transporters.
Schaedler TA, Faust B, Shintre CA, Carpenter EP, Srinivasan V, van Veen HW, Balk J. Schaedler TA, et al. Among authors: carpenter ep. Biochem Soc Trans. 2015 Oct;43(5):943-51. doi: 10.1042/BST20150118. Biochem Soc Trans. 2015. PMID: 26517908 Review.
Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states.
Shintre CA, Pike AC, Li Q, Kim JI, Barr AJ, Goubin S, Shrestha L, Yang J, Berridge G, Ross J, Stansfeld PJ, Sansom MS, Edwards AM, Bountra C, Marsden BD, von Delft F, Bullock AN, Gileadi O, Burgess-Brown NA, Carpenter EP. Shintre CA, et al. Among authors: carpenter ep. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9710-5. doi: 10.1073/pnas.1217042110. Epub 2013 May 28. Proc Natl Acad Sci U S A. 2013. PMID: 23716676 Free PMC article.
Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).
Grieben M, Pike AC, Shintre CA, Venturi E, El-Ajouz S, Tessitore A, Shrestha L, Mukhopadhyay S, Mahajan P, Chalk R, Burgess-Brown NA, Sitsapesan R, Huiskonen JT, Carpenter EP. Grieben M, et al. Among authors: carpenter ep. Nat Struct Mol Biol. 2017 Feb;24(2):114-122. doi: 10.1038/nsmb.3343. Epub 2016 Dec 19. Nat Struct Mol Biol. 2017. PMID: 27991905
The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Bushell SR, Pike ACW, Falzone ME, Rorsman NJG, Ta CM, Corey RA, Newport TD, Christianson JC, Scofano LF, Shintre CA, Tessitore A, Chu A, Wang Q, Shrestha L, Mukhopadhyay SMM, Love JD, Burgess-Brown NA, Sitsapesan R, Stansfeld PJ, Huiskonen JT, Tammaro P, Accardi A, Carpenter EP. Bushell SR, et al. Among authors: carpenter ep. Nat Commun. 2019 Sep 2;10(1):3956. doi: 10.1038/s41467-019-11753-1. Nat Commun. 2019. PMID: 31477691 Free PMC article.
Asymmetric mechanosensitivity in a eukaryotic ion channel.
Clausen MV, Jarerattanachat V, Carpenter EP, Sansom MSP, Tucker SJ. Clausen MV, et al. Among authors: carpenter ep. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8343-E8351. doi: 10.1073/pnas.1708990114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923939 Free PMC article.
Insights into how nucleotide-binding domains power ABC transport.
Newstead S, Fowler PW, Bilton P, Carpenter EP, Sadler PJ, Campopiano DJ, Sansom MS, Iwata S. Newstead S, et al. Among authors: carpenter ep. Structure. 2009 Sep 9;17(9):1213-22. doi: 10.1016/j.str.2009.07.009. Structure. 2009. PMID: 19748342 Free PMC article.
Molecular insights into lipid-assisted Ca2+ regulation of the TRP channel Polycystin-2.
Wilkes M, Madej MG, Kreuter L, Rhinow D, Heinz V, De Sanctis S, Ruppel S, Richter RM, Joos F, Grieben M, Pike AC, Huiskonen JT, Carpenter EP, Kühlbrandt W, Witzgall R, Ziegler C. Wilkes M, et al. Among authors: carpenter ep. Nat Struct Mol Biol. 2017 Feb;24(2):123-130. doi: 10.1038/nsmb.3357. Epub 2017 Jan 16. Nat Struct Mol Biol. 2017. PMID: 28092368
52 results