Gifford DK - Search Results

1

Generative modeling of single-cell time series with PRESCIENT enables prediction of cell trajectories with interventions.

Yeo GHT, Saksena SD, Gifford DK. Yeo GHT, et al. Among authors: gifford dk. Nat Commun. 2021 May 28;12(1):3222. doi: 10.1038/s41467-021-23518-w. Nat Commun. 2021. PMID: 34050150 Free PMC article.

2

Predictable and precise template-free CRISPR editing of pathogenic variants.

Shen MW, Arbab M, Hsu JY, Worstell D, Culbertson SJ, Krabbe O, Cassa CA, Liu DR, Gifford DK, Sherwood RI. Shen MW, et al. Among authors: gifford dk. Nature. 2018 Nov;563(7733):646-651. doi: 10.1038/s41586-018-0686-x. Epub 2018 Nov 7. Nature. 2018. PMID: 30405244 Free PMC article.

3

A Multiplexed Barcodelet Single-Cell RNA-Seq Approach Elucidates Combinatorial Signaling Pathways that Drive ESC Differentiation.

Yeo GHT, Lin L, Qi CY, Cha M, Gifford DK, Sherwood RI. Yeo GHT, et al. Among authors: gifford dk. Cell Stem Cell. 2020 Jun 4;26(6):938-950.e6. doi: 10.1016/j.stem.2020.04.020. Epub 2020 May 26. Cell Stem Cell. 2020. PMID: 32459995 Free PMC article.

4

Detection of gene cis-regulatory element perturbations in single-cell transcriptomes.

Yeo GHT, Juez O, Chen Q, Banerjee B, Chu L, Shen MW, Sabry M, Logister I, Sherwood RI, Gifford DK. Yeo GHT, et al. Among authors: gifford dk. PLoS Comput Biol. 2021 Mar 12;17(3):e1008789. doi: 10.1371/journal.pcbi.1008789. eCollection 2021 Mar. PLoS Comput Biol. 2021. PMID: 33711017 Free PMC article.

5

Small molecule inhibition of ATM kinase increases CRISPR-Cas9 1-bp insertion frequency.

Bermudez-Cabrera HC, Culbertson S, Barkal S, Holmes B, Shen MW, Zhang S, Gifford DK, Sherwood RI. Bermudez-Cabrera HC, et al. Among authors: gifford dk. Nat Commun. 2021 Aug 25;12(1):5111. doi: 10.1038/s41467-021-25415-8. Nat Commun. 2021. PMID: 34433825 Free PMC article.

6

Ranking reprogramming factors for cell differentiation.

Hammelman J, Patel T, Closser M, Wichterle H, Gifford D. Hammelman J, et al. Nat Methods. 2022 Jul;19(7):812-822. doi: 10.1038/s41592-022-01522-2. Epub 2022 Jun 16. Nat Methods. 2022. PMID: 35710610 Free PMC article.

7

Ultra-high-diversity factorizable libraries for efficient therapeutic discovery.

Dai Z, Saksena SD, Horny G, Banholzer C, Ewert S, Gifford DK. Dai Z, et al. Among authors: gifford dk. Genome Res. 2022 Jun 23;32(9):1787-94. doi: 10.1101/gr.276593.122. Online ahead of print. Genome Res. 2022. PMID: 35738900 Free PMC article.

8

Computational counterselection identifies nonspecific therapeutic biologic candidates.

Saksena SD, Liu G, Banholzer C, Horny G, Ewert S, Gifford DK. Saksena SD, et al. Among authors: gifford dk. Cell Rep Methods. 2022 Jul 11;2(7):100254. doi: 10.1016/j.crmeth.2022.100254. eCollection 2022 Jul 18. Cell Rep Methods. 2022. PMID: 35880012 Free PMC article.

9

Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro.

Patel T, Hammelman J, Aziz S, Jang S, Closser M, Michaels TL, Blum JA, Gifford DK, Wichterle H. Patel T, et al. Among authors: gifford dk. Nat Commun. 2022 Sep 15;13(1):5427. doi: 10.1038/s41467-022-33022-4. Nat Commun. 2022. PMID: 36109497 Free PMC article.

10

Bayesian network approach to cell signaling pathway modeling.

Sachs K, Gifford D, Jaakkola T, Sorger P, Lauffenburger DA. Sachs K, et al. Sci STKE. 2002 Sep 3;2002(148):pe38. doi: 10.1126/stke.2002.148.pe38. Sci STKE. 2002. PMID: 12209052

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