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Intrathecal Immunoglobulin M Synthesis is an Independent Biomarker for Higher Disease Activity and Severity in Multiple Sclerosis.
Oechtering J, Schaedelin S, Benkert P, Müller S, Achtnichts L, Vehoff J, Disanto G, Findling O, Fischer-Barnicol B, Orleth A, Chan A, Pot C, Barakovic M, Rahmanzadeh R, Galbusera R, Heijnen I, Lalive PH, Wuerfel J, Subramaniam S, Aeschbacher S, Conen D, Naegelin Y, Maceski A, Meier S, Berger K, Wiendl H, Lincke T, Lieb J, Yaldizli Ö, Sinnecker T, Derfuss T, Regeniter A, Zecca C, Gobbi C, Kappos L, Granziera C, Leppert D, Kuhle J; Swiss Multiple Sclerosis Cohort Study. Oechtering J, et al. Among authors: heijnen i. Ann Neurol. 2021 Sep;90(3):477-489. doi: 10.1002/ana.26137. Epub 2021 Jun 22. Ann Neurol. 2021. PMID: 34057235 Free PMC article.
Intrathecal IgM Synthesis Is Associated with Spinal Cord Manifestation and Neuronal Injury in Early MS.
Oechtering J, Lincke T, Schaedelin S, Décard BF, Maceski A, Orleth A, Meier S, Willemse E, Buchmann A, Khalil M, Derfuss T, Benkert P, Heijnen I, Regeniter A, Müller S, Achtnichts L, Lalive P, Salmen A, Pot C, Gobbi C, Kappos L, Granziera C, Leppert D, Schlaeger R, Lieb JM, Kuhle J; Swiss MS Cohort Study. Oechtering J, et al. Among authors: heijnen i. Ann Neurol. 2022 Jun;91(6):814-820. doi: 10.1002/ana.26348. Epub 2022 Apr 9. Ann Neurol. 2022. PMID: 35293622 Free PMC article.
Facial nerve palsy and anti-Ku autoantibodies.
Sutter R, Mengiardi B, Benz D, Heijnen I, Kappos L, Winkler DT. Sutter R, et al. Among authors: heijnen i. J Neurol. 2012 Feb;259(2):361-3. doi: 10.1007/s00415-011-6166-y. Epub 2011 Jul 18. J Neurol. 2012. PMID: 21769532 No abstract available.
Prediction of Acute COPD Exacerbation in the Swiss Multicenter COPD Cohort Study (TOPDOCS) by Clinical Parameters, Medication Use, and Immunological Biomarkers.
Huebner ST, Henny S, Giezendanner S, Brack T, Brutsche M, Chhajed P, Clarenbach C, Dieterle T, Egli A, Frey M, Heijnen I, Irani S, Sievi NA, Thurnheer R, Trendelenburg M, Kohler M, Leuppi-Taegtmeyer AB, Leuppi JD. Huebner ST, et al. Among authors: heijnen i. Respiration. 2022;101(5):441-454. doi: 10.1159/000520196. Epub 2021 Dec 23. Respiration. 2022. PMID: 34942619 Free PMC article.
Low immunoglobulin E flags two distinct types of immune dysregulation.
Elkuch M, Greiff V, Berger CT, Bouchenaki M, Daikeler T, Bircher A, Navarini AA, Heijnen I, Recher M. Elkuch M, et al. Among authors: heijnen i. Clin Exp Immunol. 2017 Mar;187(3):345-352. doi: 10.1111/cei.12885. Epub 2017 Jan 11. Clin Exp Immunol. 2017. PMID: 28078662 Free PMC article.
Anti-C1q antibodies as a follow-up marker in SLE patients.
Bock M, Heijnen I, Trendelenburg M. Bock M, et al. Among authors: heijnen i. PLoS One. 2015 Apr 16;10(4):e0123572. doi: 10.1371/journal.pone.0123572. eCollection 2015. PLoS One. 2015. PMID: 25881125 Free PMC article.
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