Wang ET - Search Results

1

Molecular mechanisms underlying nucleotide repeat expansion disorders.

Malik I, Kelley CP, Wang ET, Todd PK. Malik I, et al. Among authors: wang et. Nat Rev Mol Cell Biol. 2021 Sep;22(9):589-607. doi: 10.1038/s41580-021-00382-6. Epub 2021 Jun 17. Nat Rev Mol Cell Biol. 2021. PMID: 34140671 Free PMC article. Review.

2

Myotonic dystrophy: approach to therapy.

Thornton CA, Wang E, Carrell EM. Thornton CA, et al. Curr Opin Genet Dev. 2017 Jun;44:135-140. doi: 10.1016/j.gde.2017.03.007. Epub 2017 Apr 1. Curr Opin Genet Dev. 2017. PMID: 28376341 Free PMC article. Review.

3

A Defective mRNA Cleavage and Polyadenylation Complex Facilitates Expansions of Transcribed (GAA)_n Repeats Associated with Friedreich's Ataxia.

McGinty RJ, Puleo F, Aksenova AY, Hisey JA, Shishkin AA, Pearson EL, Wang ET, Housman DE, Moore C, Mirkin SM. McGinty RJ, et al. Among authors: wang et. Cell Rep. 2017 Sep 5;20(10):2490-2500. doi: 10.1016/j.celrep.2017.08.051. Cell Rep. 2017. PMID: 28877480 Free PMC article.

4

Impeding Transcription of Expanded Microsatellite Repeats by Deactivated Cas9.

Pinto BS, Saxena T, Oliveira R, Méndez-Gómez HR, Cleary JD, Denes LT, McConnell O, Arboleda J, Xia G, Swanson MS, Wang ET. Pinto BS, et al. Among authors: wang et. Mol Cell. 2017 Nov 2;68(3):479-490.e5. doi: 10.1016/j.molcel.2017.09.033. Epub 2017 Oct 19. Mol Cell. 2017. PMID: 29056323 Free PMC article.

5

Aberrant Myokine Signaling in Congenital Myotonic Dystrophy.

Nakamori M, Hamanaka K, Thomas JD, Wang ET, Hayashi YK, Takahashi MP, Swanson MS, Nishino I, Mochizuki H. Nakamori M, et al. Among authors: wang et. Cell Rep. 2017 Oct 31;21(5):1240-1252. doi: 10.1016/j.celrep.2017.10.018. Cell Rep. 2017. PMID: 29091763 Free PMC article.

6

Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model.

Angelbello AJ, Rzuczek SG, Mckee KK, Chen JL, Olafson H, Cameron MD, Moss WN, Wang ET, Disney MD. Angelbello AJ, et al. Among authors: wang et. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7799-7804. doi: 10.1073/pnas.1901484116. Epub 2019 Mar 29. Proc Natl Acad Sci U S A. 2019. PMID: 30926669 Free PMC article.

7

Cell-type-specific dysregulation of RNA alternative splicing in short tandem repeat mouse knockin models of myotonic dystrophy.

Nutter CA, Bubenik JL, Oliveira R, Ivankovic F, Sznajder ŁJ, Kidd BM, Pinto BS, Otero BA, Carter HA, Vitriol EA, Wang ET, Swanson MS. Nutter CA, et al. Among authors: wang et. Genes Dev. 2019 Dec 1;33(23-24):1635-1640. doi: 10.1101/gad.328963.119. Epub 2019 Oct 17. Genes Dev. 2019. PMID: 31624084 Free PMC article.

8

A Toxic RNA Catalyzes the Cellular Synthesis of Its Own Inhibitor, Shunting It to Endogenous Decay Pathways.

Benhamou RI, Angelbello AJ, Wang ET, Disney MD. Benhamou RI, et al. Among authors: wang et. Cell Chem Biol. 2020 Feb 20;27(2):223-231.e4. doi: 10.1016/j.chembiol.2020.01.003. Epub 2020 Jan 24. Cell Chem Biol. 2020. PMID: 31981476 Free PMC article.

9

Repeat length increases disease penetrance and severity in C9orf72 ALS/FTD BAC transgenic mice.

Pattamatta A, Nguyen L, Olafson HR, Scotti MM, Laboissonniere LA, Richardson J, Berglund JA, Zu T, Wang ET, Ranum LPW. Pattamatta A, et al. Among authors: wang et. Hum Mol Genet. 2021 Feb 25;29(24):3900-3918. doi: 10.1093/hmg/ddaa279. Hum Mol Genet. 2021. PMID: 33378537 Free PMC article.

10

Goals in tension: motivated by genetic disease yet rooted in basic science.

Wang ET. Wang ET. Nat Rev Mol Cell Biol. 2021 Sep;22(9):581-582. doi: 10.1038/s41580-021-00395-1. Nat Rev Mol Cell Biol. 2021. PMID: 34183812 No abstract available.

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