Schaller S - Search Results

1

Safer chemicals using less animals: kick-off of the European ONTOX project.

Vinken M, Benfenati E, Busquet F, Castell J, Clevert DA, de Kok TM, Dirven H, Fritsche E, Geris L, Gozalbes R, Hartung T, Jennen D, Jover R, Kandarova H, Kramer N, Krul C, Luechtefeld T, Masereeuw R, Roggen E, Schaller S, Vanhaecke T, Yang C, Piersma AH. Vinken M, et al. Among authors: schaller s. Toxicology. 2021 Jun 30;458:152846. doi: 10.1016/j.tox.2021.152846. Epub 2021 Jun 30. Toxicology. 2021. PMID: 34216698 Free article. Review.

2

Systematic evaluation of high-throughput PBK modelling strategies for the prediction of intravenous and oral pharmacokinetics in humans.

Geci R, Gadaleta D, de Lomana MG, Ortega-Vallbona R, Colombo E, Serrano-Candelas E, Paini A, Kuepfer L, Schaller S. Geci R, et al. Among authors: schaller s. Arch Toxicol. 2024 May 9. doi: 10.1007/s00204-024-03764-9. Online ahead of print. Arch Toxicol. 2024. PMID: 38722347

3

Considering developmental neurotoxicity in vitro data for human health risk assessment using physiologically-based kinetic modeling: deltamethrin case study.

Maass C, Schaller S, Dallmann A, Bothe K, Müller D. Maass C, et al. Among authors: schaller s. Toxicol Sci. 2023 Mar 20;192(1):59-70. doi: 10.1093/toxsci/kfad007. Toxicol Sci. 2023. PMID: 36637193 Free PMC article.

4

A generic avian physiologically-based kinetic (PBK) model and its application in three bird species.

Baier V, Paini A, Schaller S, Scanes CG, Bone AJ, Ebeling M, Preuss TG, Witt J, Heckmann D. Baier V, et al. Among authors: schaller s. Environ Int. 2022 Nov;169:107547. doi: 10.1016/j.envint.2022.107547. Epub 2022 Sep 26. Environ Int. 2022. PMID: 36179644 Free article.

5

A Physiologically-Based Quantitative Systems Pharmacology Model of the Incretin Hormones GLP-1 and GIP and the DPP4 Inhibitor Sitagliptin.

Balazki P, Schaller S, Eissing T, Lehr T. Balazki P, et al. Among authors: schaller s. CPT Pharmacometrics Syst Pharmacol. 2020 Jun;9(6):353-362. doi: 10.1002/psp4.12520. Epub 2020 Jun 16. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 32543789 Free PMC article.

6

Quantitative Comparison of Avian and Mammalian Physiologies for Parameterization of Physiologically Based Kinetic Models.

Scanes CG, Witt J, Ebeling M, Schaller S, Baier V, Bone AJ, Preuss TG, Heckmann D. Scanes CG, et al. Among authors: schaller s. Front Physiol. 2022 Apr 5;13:858386. doi: 10.3389/fphys.2022.858386. eCollection 2022. Front Physiol. 2022. PMID: 35450159 Free PMC article.

7

Quantitative Morphometric, Physiological, and Metabolic Characteristics of Chickens and Mallards for Physiologically Based Kinetic Model Development.

Scanes CG, Witt J, Ebeling M, Schaller S, Baier V, Bone AJ, Preuss TG, Heckmann D. Scanes CG, et al. Among authors: schaller s. Front Physiol. 2022 Apr 6;13:858283. doi: 10.3389/fphys.2022.858283. eCollection 2022. Front Physiol. 2022. PMID: 35464078 Free PMC article.

8

A Generic Integrated Physiologically based Whole-body Model of the Glucose-Insulin-Glucagon Regulatory System.

Schaller S, Willmann S, Lippert J, Schaupp L, Pieber TR, Schuppert A, Eissing T. Schaller S, et al. CPT Pharmacometrics Syst Pharmacol. 2013 Aug 14;2(8):e65. doi: 10.1038/psp.2013.40. CPT Pharmacometrics Syst Pharmacol. 2013. PMID: 23945606 Free PMC article.

9

Evaluation of the drug-drug interaction potential of treosulfan using a physiologically-based pharmacokinetic modelling approach.

Schaller S, Martins FS, Balazki P, Böhm S, Baumgart J, Hilger RA, Beelen DW, Hemmelmann C, Ring A. Schaller S, et al. Br J Clin Pharmacol. 2022 Feb;88(4):1722-1734. doi: 10.1111/bcp.15081. Epub 2021 Oct 13. Br J Clin Pharmacol. 2022. PMID: 34519068 Free PMC article.

10

Integrating cellular metabolism into a multiscale whole-body model.

Krauss M, Schaller S, Borchers S, Findeisen R, Lippert J, Kuepfer L. Krauss M, et al. Among authors: schaller s. PLoS Comput Biol. 2012;8(10):e1002750. doi: 10.1371/journal.pcbi.1002750. Epub 2012 Oct 25. PLoS Comput Biol. 2012. PMID: 23133351 Free PMC article.

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