Chłoń-Rzepa G - Search Results

1

A new class of 5-HT_1A receptor antagonists with procognitive and antidepressant properties.

Jankowska A, Satała G, Świerczek A, Pociecha K, Partyka A, Jastrzębska-Więsek M, Głuch-Lutwin M, Bojarski AJ, Wyska E, Chłoń-Rzepa G. Jankowska A, et al. Among authors: chlon rzepa g. Future Med Chem. 2021 Sep;13(18):1497-1514. doi: 10.4155/fmc-2020-0363. Epub 2021 Jul 13. Future Med Chem. 2021. PMID: 34253032

2

Preliminary study on application of impregnated synthetic peptide TLC stationary phases for the pre-screening of 5-HT1A ligands.

Zajdel P, Bojarski AJ, Byrtus H, Chłoń-Rzepa G, Obniska J, Chevallet P, Martinez J, Pawłowski M. Zajdel P, et al. Biomed Chromatogr. 2003 Jul;17(5):312-7. doi: 10.1002/bmc.224. Biomed Chromatogr. 2003. PMID: 12884396

3

7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT(1A), 5-HT(2A), and 5-HT(7) serotonin receptor ligands.

Chłoń-Rzepa G, Zmudzki P, Zajdel P, Bojarski AJ, Duszyńska B, Nikiforuk A, Tatarczyńska E, Pawłowski M. Chłoń-Rzepa G, et al. Bioorg Med Chem. 2007 Aug 1;15(15):5239-50. doi: 10.1016/j.bmc.2007.05.017. Epub 2007 May 10. Bioorg Med Chem. 2007. PMID: 17517514

4

New 8-aminoalkyl derivatives of purine-2,6-dione with arylalkyl, allyl or propynyl substituents in position 7, their 5-HT1A, 5-HT2A, and 5-HT7 receptor affinity and pharmacological evaluation.

Chłoń-Rzepa G, Zmudzki P, Satała G, Duszyńska B, Partyka A, Wróbel D, Jastrzębska-Więsek M, Wesołowska A, Bojarski AJ, Pawłowski M, Zajdel P. Chłoń-Rzepa G, et al. Pharmacol Rep. 2013;65(1):15-29. doi: 10.1016/s1734-1140(13)70960-5. Pharmacol Rep. 2013. PMID: 23563020 Free article.

5

7-3-Chlorophenypiperazinylalkyl derivatives of 8-alkoxy-purine-2,6-dione as a serotonin receptor ligands with potential antidepressant activity.

Zygmunt M, Sapa J, Chłoń-Rzepa G, Zagórska A, Siwek A, Pawłowski M, Nowak G. Zygmunt M, et al. Pharmacol Rep. 2014 Jun;66(3):505-10. doi: 10.1016/j.pharep.2013.12.014. Epub 2014 Apr 13. Pharmacol Rep. 2014. PMID: 24905531

6

Antidepressant- and anxiolytic-like activity of 7-phenylpiperazinylalkyl-1,3-dimethyl-purine-2,6-dione derivatives with diversified 5-HT₁A receptor functional profile.

Partyka A, Chłoń-Rzepa G, Wasik A, Jastrzębska-Więsek M, Bucki A, Kołaczkowski M, Satała G, Bojarski AJ, Wesołowska A. Partyka A, et al. Bioorg Med Chem. 2015 Jan 1;23(1):212-21. doi: 10.1016/j.bmc.2014.11.008. Epub 2014 Nov 11. Bioorg Med Chem. 2015. PMID: 25435254

7

Structure-5-HT receptor affinity relationship in a new group of 7-arylpiperazynylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-amino-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione.

Żmudzki P, Chłoń-Rzepa G, Bojarski AJ, Zygmunt M, Kazek G, Mordyl B, Pawłowski M. Żmudzki P, et al. Arch Pharm (Weinheim). 2015 Apr;348(4):229-41. doi: 10.1002/ardp.201400392. Epub 2015 Mar 13. Arch Pharm (Weinheim). 2015. PMID: 25773578

8

New arylpiperazinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and dihydro[1,3]oxazolo[2,3-f]purinedione targeting the serotonin 5-HT1A /5-HT2A /5-HT7 and dopamine D2 receptors.

Chłoń-Rzepa G, Zagórska A, Bucki A, Kołaczkowski M, Pawłowski M, Satała G, Bojarski AJ, Partyka A, Wesołowska A, Pękala E, Słoczyńska K. Chłoń-Rzepa G, et al. Arch Pharm (Weinheim). 2015 Apr;348(4):242-53. doi: 10.1002/ardp.201500015. Epub 2015 Mar 13. Arch Pharm (Weinheim). 2015. PMID: 25773907

9

Arylpiperazinylalkyl derivatives of 8-amino-1,3-dimethylpurine-2,6-dione as novel multitarget 5-HT/D receptor agents with potential antipsychotic activity.

Chłoń-Rzepa G, Bucki A, Kołaczkowski M, Partyka A, Jastrzębska-Więsek M, Satała G, Bojarski AJ, Kalinowska-Tłuścik J, Kazek G, Mordyl B, Głuch-Lutwin M, Wesołowska A. Chłoń-Rzepa G, et al. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1048-62. doi: 10.3109/14756366.2015.1088844. Epub 2015 Sep 25. J Enzyme Inhib Med Chem. 2016. PMID: 26406608

10

ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITY OF 8-METHOXY-1,3-DIMETHYL-2,6-DIOXO-PURIN-7-YL DERIVATIVES WITH TERMINAL CARBOXYLIC, ESTER OR AMIDE MOIETIES IN ANIMAL MODELS.

Zygmunt M, Chłon-Rzepa G, Wyska E, Pociecha K, Sapa J. Zygmunt M, et al. Acta Pol Pharm. 2016 May-Jun;73(3):761-70. Acta Pol Pharm. 2016. PMID: 27476295

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