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FANCI functions as a repair/apoptosis switch in response to DNA crosslinks.
Shah RB, Kernan JL, van Hoogstraten A, Ando K, Li Y, Belcher AL, Mininger I, Bussenault AM, Raman R, Ramanagoudr-Bhojappa R, Huang TT, D'Andrea AD, Chandrasekharappa SC, Aggarwal AK, Thompson R, Sidi S. Shah RB, et al. Among authors: sidi s. Dev Cell. 2021 Aug 9;56(15):2207-2222.e7. doi: 10.1016/j.devcel.2021.06.010. Epub 2021 Jul 12. Dev Cell. 2021. PMID: 34256011 Free PMC article.
An Inhibitor of PIDDosome Formation.
Thompson R, Shah RB, Liu PH, Gupta YK, Ando K, Aggarwal AK, Sidi S. Thompson R, et al. Among authors: sidi s. Mol Cell. 2015 Jun 4;58(5):767-79. doi: 10.1016/j.molcel.2015.03.034. Epub 2015 Apr 30. Mol Cell. 2015. PMID: 25936804 Free PMC article.
NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus.
Ando K, Parsons MJ, Shah RB, Charendoff CI, Paris SL, Liu PH, Fassio SR, Rohrman BA, Thompson R, Oberst A, Sidi S, Bouchier-Hayes L. Ando K, et al. Among authors: sidi s. J Cell Biol. 2017 Jun 5;216(6):1795-1810. doi: 10.1083/jcb.201608095. Epub 2017 Apr 21. J Cell Biol. 2017. PMID: 28432080 Free PMC article.
An IRAK1-PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy.
Liu PH, Shah RB, Li Y, Arora A, Ung PM, Raman R, Gorbatenko A, Kozono S, Zhou XZ, Brechin V, Barbaro JM, Thompson R, White RM, Aguirre-Ghiso JA, Heymach JV, Lu KP, Silva JM, Panageas KS, Schlessinger A, Maki RG, Skinner HD, de Stanchina E, Sidi S. Liu PH, et al. Among authors: sidi s. Nat Cell Biol. 2019 Feb;21(2):203-213. doi: 10.1038/s41556-018-0260-7. Epub 2019 Jan 21. Nat Cell Biol. 2019. PMID: 30664786 Free PMC article.
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo.
Dubiella C, Pinch BJ, Koikawa K, Zaidman D, Poon E, Manz TD, Nabet B, He S, Resnick E, Rogel A, Langer EM, Daniel CJ, Seo HS, Chen Y, Adelmant G, Sharifzadeh S, Ficarro SB, Jamin Y, Martins da Costa B, Zimmerman MW, Lian X, Kibe S, Kozono S, Doctor ZM, Browne CM, Yang A, Stoler-Barak L, Shah RB, Vangos NE, Geffken EA, Oren R, Koide E, Sidi S, Shulman Z, Wang C, Marto JA, Dhe-Paganon S, Look T, Zhou XZ, Lu KP, Sears RC, Chesler L, Gray NS, London N. Dubiella C, et al. Among authors: sidi s. Nat Chem Biol. 2021 Sep;17(9):954-963. doi: 10.1038/s41589-021-00786-7. Epub 2021 May 10. Nat Chem Biol. 2021. PMID: 33972797 Free PMC article.
36 results