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Deacetylation as a receptor-regulated direct activation switch for pannexin channels.
Chiu YH, Medina CB, Doyle CA, Zhou M, Narahari AK, Sandilos JK, Gonye EC, Gao HY, Guo SY, Parlak M, Lorenz UM, Conrads TP, Desai BN, Ravichandran KS, Bayliss DA. Chiu YH, et al. Among authors: sandilos jk. Nat Commun. 2021 Jul 23;12(1):4482. doi: 10.1038/s41467-021-24825-y. Nat Commun. 2021. PMID: 34301959 Free PMC article.
A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells.
Billaud M, Chiu YH, Lohman AW, Parpaite T, Butcher JT, Mutchler SM, DeLalio LJ, Artamonov MV, Sandilos JK, Best AK, Somlyo AV, Thompson RJ, Le TH, Ravichandran KS, Bayliss DA, Isakson BE. Billaud M, et al. Among authors: sandilos jk. Sci Signal. 2015 Feb 17;8(364):ra17. doi: 10.1126/scisignal.2005824. Sci Signal. 2015. PMID: 25690012 Free PMC article.
Pannexin 1 is required for full activation of insulin-stimulated glucose uptake in adipocytes.
Adamson SE, Meher AK, Chiu YH, Sandilos JK, Oberholtzer NP, Walker NN, Hargett SR, Seaman SA, Peirce-Cottler SM, Isakson BE, McNamara CA, Keller SR, Harris TE, Bayliss DA, Leitinger N. Adamson SE, et al. Among authors: sandilos jk. Mol Metab. 2015 Jul 3;4(9):610-8. doi: 10.1016/j.molmet.2015.06.009. eCollection 2015 Sep. Mol Metab. 2015. PMID: 26413467 Free PMC article.
S-nitrosylation inhibits pannexin 1 channel function.
Lohman AW, Weaver JL, Billaud M, Sandilos JK, Griffiths R, Straub AC, Penuela S, Leitinger N, Laird DW, Bayliss DA, Isakson BE. Lohman AW, et al. Among authors: sandilos jk. J Biol Chem. 2012 Nov 16;287(47):39602-12. doi: 10.1074/jbc.M112.397976. Epub 2012 Oct 2. J Biol Chem. 2012. PMID: 23033481 Free PMC article.
Pannexin 1 in the regulation of vascular tone.
Billaud M, Sandilos JK, Isakson BE. Billaud M, et al. Among authors: sandilos jk. Trends Cardiovasc Med. 2012 Apr;22(3):68-72. doi: 10.1016/j.tcm.2012.06.014. Epub 2012 Jul 28. Trends Cardiovasc Med. 2012. PMID: 22841835 Free PMC article. Review.