Schuetz JD - Search Results

1

Development and validation of an LC-MS/MS method to quantify the bromodomain and extra-terminal (BET) inhibitor JQ1 in mouse plasma and brain microdialysate: Application to cerebral microdialysis study.

Nair S, Davis A, Campagne O, Schuetz JD, Stewart CF. Nair S, et al. Among authors: schuetz jd. J Pharm Biomed Anal. 2021 Sep 10;204:114274. doi: 10.1016/j.jpba.2021.114274. Epub 2021 Jul 21. J Pharm Biomed Anal. 2021. PMID: 34311284 Free PMC article.

2

Development and Validation of a Sensitive and Specific LC-MS/MS Method for IWR-1-Endo, a Wnt Signaling Inhibitor: Application to a Cerebral Microdialysis Study.

Nair S, Davis A, Campagne O, Schuetz JD, Stewart CF. Nair S, et al. Among authors: schuetz jd. Molecules. 2022 Aug 25;27(17):5448. doi: 10.3390/molecules27175448. Molecules. 2022. PMID: 36080214 Free PMC article.

3

Mrp4 confers resistance to topotecan and protects the brain from chemotherapy.

Leggas M, Adachi M, Scheffer GL, Sun D, Wielinga P, Du G, Mercer KE, Zhuang Y, Panetta JC, Johnston B, Scheper RJ, Stewart CF, Schuetz JD. Leggas M, et al. Among authors: schuetz jd. Mol Cell Biol. 2004 Sep;24(17):7612-21. doi: 10.1128/MCB.24.17.7612-7621.2004. Mol Cell Biol. 2004. PMID: 15314169 Free PMC article.

4

ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy.

Morfouace M, Cheepala S, Jackson S, Fukuda Y, Patel YT, Fatima S, Kawauchi D, Shelat AA, Stewart CF, Sorrentino BP, Schuetz JD, Roussel MF. Morfouace M, et al. Among authors: schuetz jd. Cancer Res. 2015 Sep 15;75(18):3879-89. doi: 10.1158/0008-5472.CAN-15-0030. Epub 2015 Jul 21. Cancer Res. 2015. PMID: 26199091 Free PMC article.

5

Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro.

Houghton PJ, Germain GS, Harwood FC, Schuetz JD, Stewart CF, Buchdunger E, Traxler P. Houghton PJ, et al. Among authors: schuetz jd. Cancer Res. 2004 Apr 1;64(7):2333-7. doi: 10.1158/0008-5472.can-03-3344. Cancer Res. 2004. PMID: 15059881

6

Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution.

Takenaka K, Morgan JA, Scheffer GL, Adachi M, Stewart CF, Sun D, Leggas M, Ejendal KF, Hrycyna CA, Schuetz JD. Takenaka K, et al. Among authors: schuetz jd. Cancer Res. 2007 Jul 15;67(14):6965-72. doi: 10.1158/0008-5472.CAN-06-4720. Cancer Res. 2007. PMID: 17638908

7

Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice.

Stewart CF, Leggas M, Schuetz JD, Panetta JC, Cheshire PJ, Peterson J, Daw N, Jenkins JJ 3rd, Gilbertson R, Germain GS, Harwood FC, Houghton PJ. Stewart CF, et al. Among authors: schuetz jd. Cancer Res. 2004 Oct 15;64(20):7491-9. doi: 10.1158/0008-5472.CAN-04-0096. Cancer Res. 2004. PMID: 15492275

8

Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivo.

Leggas M, Panetta JC, Zhuang Y, Schuetz JD, Johnston B, Bai F, Sorrentino B, Zhou S, Houghton PJ, Stewart CF. Leggas M, et al. Among authors: schuetz jd. Cancer Res. 2006 May 1;66(9):4802-7. doi: 10.1158/0008-5472.CAN-05-2915. Cancer Res. 2006. PMID: 16651435

9

Investigation of the Importance of Multidrug Resistance-Associated Protein 4 (Mrp4/Abcc4) in the Active Efflux of Anionic Drugs Across the Blood-Brain Barrier.

Kanamitsu K, Kusuhara H, Schuetz JD, Takeuchi K, Sugiyama Y. Kanamitsu K, et al. Among authors: schuetz jd. J Pharm Sci. 2017 Sep;106(9):2566-2575. doi: 10.1016/j.xphs.2017.04.040. Epub 2017 Apr 27. J Pharm Sci. 2017. PMID: 28456721 Free PMC article.

10

IDH1 and IDH2 mutations in pediatric acute leukemia.

Andersson AK, Miller DW, Lynch JA, Lemoff AS, Cai Z, Pounds SB, Radtke I, Yan B, Schuetz JD, Rubnitz JE, Ribeiro RC, Raimondi SC, Zhang J, Mullighan CG, Shurtleff SA, Schulman BA, Downing JR. Andersson AK, et al. Among authors: schuetz jd. Leukemia. 2011 Oct;25(10):1570-7. doi: 10.1038/leu.2011.133. Epub 2011 Jun 7. Leukemia. 2011. PMID: 21647154 Free PMC article.

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