Berasi S - Search Results

1

A Phase 1 first-in-human study of the safety, tolerability, and pharmacokinetics of the ROBO2 fusion protein PF-06730512 in healthy participants.

Lim CN, Kantaridis C, Huyghe I, Gorman D, Berasi S, Sonnenberg GE. Lim CN, et al. Among authors: berasi s. Pharmacol Res Perspect. 2021 Aug;9(4):e00813. doi: 10.1002/prp2.813. Pharmacol Res Perspect. 2021. PMID: 34369667 Free PMC article. Clinical Trial.

2

PODO: Trial Design: Phase 2 Study of PF-06730512 in Focal Segmental Glomerulosclerosis.

Beck LH Jr, Berasi SP, Copley JB, Gorman D, Levy DI, Lim CN, Henderson JM, Salant DJ, Lu W. Beck LH Jr, et al. Among authors: berasi sp. Kidney Int Rep. 2021 Apr 3;6(6):1629-1633. doi: 10.1016/j.ekir.2021.03.892. eCollection 2021 Jun. Kidney Int Rep. 2021. PMID: 34169203 Free PMC article.

3

Development of a Cell-Based Assay for the Detection of Neutralizing Antibodies to PF-06730512 Using Homogenous Time-Resolved Fluorescence.

Luong M, Wang Y, Berasi SP, Buhlmann JE, Yang H, Gorovits B. Luong M, et al. Among authors: berasi sp. AAPS J. 2020 Mar 12;22(2):56. doi: 10.1208/s12248-020-0431-x. AAPS J. 2020. PMID: 32166588

4

Loss of Roundabout Guidance Receptor 2 (Robo2) in Podocytes Protects Adult Mice from Glomerular Injury by Maintaining Podocyte Foot Process Structure.

Pisarek-Horowitz A, Fan X, Kumar S, Rasouly HM, Sharma R, Chen H, Coser K, Bluette CT, Hirenallur-Shanthappa D, Anderson SR, Yang H, Beck LH Jr, Bonegio RG, Henderson JM, Berasi SP, Salant DJ, Lu W. Pisarek-Horowitz A, et al. Among authors: berasi sp. Am J Pathol. 2020 Apr;190(4):799-816. doi: 10.1016/j.ajpath.2019.12.009. Epub 2020 Mar 24. Am J Pathol. 2020. PMID: 32220420 Free PMC article.

5

SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion.

Fan X, Yang H, Kumar S, Tumelty KE, Pisarek-Horowitz A, Rasouly HM, Sharma R, Chan S, Tyminski E, Shamashkin M, Belghasem M, Henderson JM, Coyle AJ, Salant DJ, Berasi SP, Lu W. Fan X, et al. Among authors: berasi sp. JCI Insight. 2016 Nov 17;1(19):e86934. doi: 10.1172/jci.insight.86934. JCI Insight. 2016. PMID: 27882344 Free PMC article.

6

A Retrospective Study of Clinical and Economic Burden of Focal Segmental Glomerulosclerosis (FSGS) in the United States.

Kalantar-Zadeh K, Baker CL, Copley JB, Levy DI, Berasi S, Tamimi N, Alvir J, Udani SM. Kalantar-Zadeh K, et al. Among authors: berasi s. Kidney Int Rep. 2021 Aug 9;6(10):2679-2688. doi: 10.1016/j.ekir.2021.07.030. eCollection 2021 Oct. Kidney Int Rep. 2021. PMID: 34622107 Free PMC article.

7

TLR Stimulation Produces IFN-β as the Primary Driver of IFN Signaling in Nonlymphoid Primary Human Cells.

Nistler R, Sharma A, Meeth K, Huard C, Loreth C, Kalbasi A, Tyminski E, Bellmore R, Coyle AJ, Gullà SV, Berasi SP, Greenberg SA, Buhlmann JE. Nistler R, et al. Among authors: berasi sp. Immunohorizons. 2020 Jun 18;4(6):332-338. doi: 10.4049/immunohorizons.1800054. Immunohorizons. 2020. PMID: 32554437 Free article.

8

Identification of direct negative cross-talk between the SLIT2 and bone morphogenetic protein-Gremlin signaling pathways.

Tumelty KE, Higginson-Scott N, Fan X, Bajaj P, Knowlton KM, Shamashkin M, Coyle AJ, Lu W, Berasi SP. Tumelty KE, et al. Among authors: berasi sp. J Biol Chem. 2018 Mar 2;293(9):3039-3055. doi: 10.1074/jbc.M117.804021. Epub 2018 Jan 9. J Biol Chem. 2018. PMID: 29317497 Free PMC article.

9

A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.

Seeherman HJ, Berasi SP, Brown CT, Martinez RX, Juo ZS, Jelinsky S, Cain MJ, Grode J, Tumelty KE, Bohner M, Grinberg O, Orr N, Shoseyov O, Eyckmans J, Chen C, Morales PR, Wilson CG, Vanderploeg EJ, Wozney JM. Seeherman HJ, et al. Among authors: berasi sp. Sci Transl Med. 2019 Apr 24;11(489):eaar4953. doi: 10.1126/scitranslmed.aar4953. Sci Transl Med. 2019. PMID: 31019025

10

Estrogen-related receptor α regulates osteoblast differentiation via Wnt/β-catenin signaling.

Auld KL, Berasi SP, Liu Y, Cain M, Zhang Y, Huard C, Fukayama S, Zhang J, Choe S, Zhong W, Bhat BM, Bhat RA, Brown EL, Martinez RV. Auld KL, et al. Among authors: berasi sp. J Mol Endocrinol. 2012 Mar 12;48(2):177-91. doi: 10.1530/JME-11-0140. Print 2012 Apr. J Mol Endocrinol. 2012. PMID: 22333182

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