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JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors.
Gao SP, Chang Q, Mao N, Daly LA, Vogel R, Chan T, Liu SH, Bournazou E, Schori E, Zhang H, Brewer MR, Pao W, Morris L, Ladanyi M, Arcila M, Manova-Todorova K, de Stanchina E, Norton L, Levine RL, Altan-Bonnet G, Solit D, Zinda M, Huszar D, Lyden D, Bromberg JF. Gao SP, et al. Among authors: mao n. Sci Signal. 2016 Mar 29;9(421):ra33. doi: 10.1126/scisignal.aac8460. Sci Signal. 2016. PMID: 27025877 Free PMC article.
Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors.
Kaittanis C, Andreou C, Hieronymus H, Mao N, Foss CA, Eiber M, Weirich G, Panchal P, Gopalan A, Zurita J, Achilefu S, Chiosis G, Ponomarev V, Schwaiger M, Carver BS, Pomper MG, Grimm J. Kaittanis C, et al. Among authors: mao n. J Exp Med. 2018 Jan 2;215(1):159-175. doi: 10.1084/jem.20171052. Epub 2017 Nov 15. J Exp Med. 2018. PMID: 29141866 Free PMC article.
Oncogenic ERG Represses PI3K Signaling through Downregulation of IRS2.
Mao N, Gao D, Hu W, Gadal S, Hieronymus H, Wang S, Lee YS, Sullivan P, Zhang Z, Choi D, Rosen N, Sawyers CL, Gopalan A, Chen Y, Carver BS. Mao N, et al. Cancer Res. 2020 Apr 1;80(7):1428-1437. doi: 10.1158/0008-5472.CAN-19-1394. Epub 2020 Feb 3. Cancer Res. 2020. PMID: 32015092 Free PMC article.
Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer.
Zhang Z, Karthaus WR, Lee YS, Gao VR, Wu C, Russo JW, Liu M, Mota JM, Abida W, Linton E, Lee E, Barnes SD, Chen HA, Mao N, Wongvipat J, Choi D, Chen X, Zhao H, Manova-Todorova K, de Stanchina E, Taplin ME, Balk SP, Rathkopf DE, Gopalan A, Carver BS, Mu P, Jiang X, Watson PA, Sawyers CL. Zhang Z, et al. Among authors: mao n. Cancer Cell. 2020 Aug 10;38(2):279-296.e9. doi: 10.1016/j.ccell.2020.06.005. Epub 2020 Jul 16. Cancer Cell. 2020. PMID: 32679108 Free PMC article.
ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming.
Li F, Yuan Q, Di W, Xia X, Liu Z, Mao N, Li L, Li C, He J, Li Y, Guo W, Zhang X, Zhu Y, Aji R, Wang S, Tong X, Ji H, Chi P, Carver B, Wang Y, Chen Y, Gao D. Li F, et al. Among authors: mao n. J Clin Invest. 2020 Nov 2;130(11):5924-5941. doi: 10.1172/JCI137967. J Clin Invest. 2020. PMID: 32701507 Free PMC article.
AKT1 E17K Inhibits Cancer Cell Migration by Abrogating β-Catenin Signaling.
Gao SP, Kiliti AJ, Zhang K, Vasani N, Mao N, Jordan E, Wise HC, Shrestha Bhattarai T, Hu W, Dorso M, Rodrigues JA, Kim K, Hanrahan AJ, Razavi P, Carver B, Chandarlapaty S, Reis-Filho JS, Taylor BS, Solit DB. Gao SP, et al. Among authors: mao n. Mol Cancer Res. 2021 Apr;19(4):573-584. doi: 10.1158/1541-7786.MCR-20-0623. Epub 2020 Dec 10. Mol Cancer Res. 2021. PMID: 33303690 Free PMC article.
Rapid interrogation of cancer cell of origin through CRISPR editing.
Feng W, Cao Z, Lim PX, Zhao H, Luo H, Mao N, Lee YS, Rivera AA, Choi D, Wu C, Han T, Romero R, de Stanchina E, Carver BS, Wang Q, Jasin M, Sawyers CL. Feng W, et al. Among authors: mao n. Proc Natl Acad Sci U S A. 2021 Aug 10;118(32):e2110344118. doi: 10.1073/pnas.2110344118. Proc Natl Acad Sci U S A. 2021. PMID: 34353917 Free PMC article.
678 results