Wu X - Search Results

1

Synthesis, structure-activity relationship and antiviral activity of indole-containing inhibitors of Flavivirus NS2B-NS3 protease.

Nie S, Zhao J, Wu X, Yao Y, Wu F, Lin YL, Li X, Kneubehl AR, Vogt MB, Rico-Hesse R, Song Y. Nie S, et al. Among authors: wu x, wu f. Eur J Med Chem. 2021 Dec 5;225:113767. doi: 10.1016/j.ejmech.2021.113767. Epub 2021 Aug 14. Eur J Med Chem. 2021. PMID: 34450494 Free PMC article.

2

Discovery, Structure-Activity Relationship, and Biological Activity of Histone-Competitive Inhibitors of Histone Acetyltransferases P300/CBP.

Wu F, Hua Y, Kaochar S, Nie S, Lin YL, Yao Y, Wu J, Wu X, Fu X, Schiff R, Davis CM, Robertson M, Ehli EA, Coarfa C, Mitsiades N, Song Y. Wu F, et al. Among authors: wu x, wu j. J Med Chem. 2020 May 14;63(9):4716-4731. doi: 10.1021/acs.jmedchem.9b02164. Epub 2020 Apr 21. J Med Chem. 2020. PMID: 32314924 Free PMC article.

3

Synthesis, Structure-Activity Relationships, and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.

Nie S, Yao Y, Wu F, Wu X, Zhao J, Hua Y, Wu J, Huo T, Lin YL, Kneubehl AR, Vogt MB, Ferreon J, Rico-Hesse R, Song Y. Nie S, et al. Among authors: wu x, wu f, wu j. J Med Chem. 2021 Mar 11;64(5):2777-2800. doi: 10.1021/acs.jmedchem.0c02070. Epub 2021 Feb 17. J Med Chem. 2021. PMID: 33596380 Free PMC article.

4

Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth.

Wu F, Nie S, Yao Y, Huo T, Li X, Wu X, Zhao J, Lin YL, Zhang Y, Mo Q, Song Y. Wu F, et al. Among authors: wu x. Theranostics. 2021 Jul 13;11(17):8172-8184. doi: 10.7150/thno.56737. eCollection 2021. Theranostics. 2021. PMID: 34373735 Free PMC article.

5

Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L.

Li X, Wu X, Nie S, Zhao J, Yao Y, Wu F, Mishra CB, Ashraf-Uz-Zaman M, Moku BK, Song Y. Li X, et al. Among authors: wu x, wu f. Cancers (Basel). 2023 Nov 3;15(21):5283. doi: 10.3390/cancers15215283. Cancers (Basel). 2023. PMID: 37958457 Free PMC article.

6

Design, synthesis and biological evaluation of 4-anilinothieno[2,3-d]pyrimidine-based hydroxamic acid derivatives as novel histone deacetylase inhibitors.

Yang W, Li L, Ji X, Wu X, Su M, Sheng L, Zang Y, Li J, Liu H. Yang W, et al. Among authors: wu x. Bioorg Med Chem. 2014 Nov 1;22(21):6146-55. doi: 10.1016/j.bmc.2014.08.030. Epub 2014 Sep 4. Bioorg Med Chem. 2014. PMID: 25261927

7

Design, synthesis and biological evaluation of isoquinoline-based derivatives as novel histone deacetylase inhibitors.

Yang W, Li L, Wang Y, Wu X, Li T, Yang N, Su M, Sheng L, Zheng M, Zang Y, Li J, Liu H. Yang W, et al. Among authors: wu x. Bioorg Med Chem. 2015 Sep 1;23(17):5881-90. doi: 10.1016/j.bmc.2015.06.071. Epub 2015 Jul 4. Bioorg Med Chem. 2015. PMID: 26211462

8

Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design.

Wang Y, Dai Y, Wu X, Li F, Liu B, Li C, Liu Q, Zhou Y, Wang B, Zhu M, Cui R, Tan X, Xiong Z, Liu J, Tan M, Xu Y, Geng M, Jiang H, Liu H, Ai J, Zheng M. Wang Y, et al. Among authors: wu x. J Med Chem. 2019 Aug 22;62(16):7473-7488. doi: 10.1021/acs.jmedchem.9b00510. Epub 2019 Aug 9. J Med Chem. 2019. PMID: 31335138

9

Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors.

Wu X, Dai M, Cui R, Wang Y, Li C, Peng X, Zhao J, Wang B, Dai Y, Feng D, Yang T, Jiang H, Geng M, Ai J, Zheng M, Liu H. Wu X, et al. Acta Pharm Sin B. 2021 Mar;11(3):781-794. doi: 10.1016/j.apsb.2020.09.002. Epub 2020 Sep 7. Acta Pharm Sin B. 2021. PMID: 33777682 Free PMC article.

10

Rhodium(III)-Catalyzed C-H Alkenylation/Directing Group Migration for the Regio- and Stereoselective Synthesis of Tetrasubstituted Alkenes.

Wu X, Lu Y, Qiao J, Dai W, Jia X, Ni H, Zhang X, Liu H, Zhao F. Wu X, et al. Org Lett. 2020 Dec 4;22(23):9163-9168. doi: 10.1021/acs.orglett.0c03077. Epub 2020 Nov 16. Org Lett. 2020. PMID: 33197189

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