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Gilteritinib Inhibits Glutamine Uptake and Utilization in FLT3-ITD-Positive AML.
Zavorka Thomas ME, Lu X, Talebi Z, Jeon JY, Buelow DR, Gibson AA, Uddin ME, Brinton LT, Nguyen J, Collins M, Lodi A, Sweeney SR, Campbell MJ, Sweet DH, Sparreboom A, Lapalombella R, Tiziani S, Baker SD. Zavorka Thomas ME, et al. Among authors: buelow dr. Mol Cancer Ther. 2021 Nov;20(11):2207-2217. doi: 10.1158/1535-7163.MCT-21-0071. Epub 2021 Sep 13. Mol Cancer Ther. 2021. PMID: 34518298 Free PMC article.
Hypoxia Reporter Element Assay.
Buelow DR, Baker SD. Buelow DR, et al. Bio Protoc. 2018 Aug 5;8(15):e2951. doi: 10.21769/BioProtoc.2951. Bio Protoc. 2018. PMID: 30899769 Free PMC article.
Preclinical activity and a pilot phase I study of pacritinib, an oral JAK2/FLT3 inhibitor, and chemotherapy in FLT3-ITD-positive AML.
Jeon JY, Zhao Q, Buelow DR, Phelps M, Walker AR, Mims AS, Vasu S, Behbehani G, Blachly J, Blum W, Klisovic RB, Byrd JC, Garzon R, Baker SD, Bhatnagar B. Jeon JY, et al. Among authors: buelow dr. Invest New Drugs. 2020 Apr;38(2):340-349. doi: 10.1007/s10637-019-00786-4. Epub 2019 May 17. Invest New Drugs. 2020. PMID: 31102119 Free PMC article. Clinical Trial.
Uncovering the Genomic Landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically Normal FLT3-ITD AML.
Buelow DR, Pounds SB, Wang YD, Shi L, Li Y, Finkelstein D, Shurtleff S, Neale G, Inaba H, Ribeiro RC, Palumbo R, Garrison D, Orwick SJ, Blachly JS, Kroll K, Byrd JC, Gruber TA, Rubnitz JE, Baker SD. Buelow DR, et al. Clin Transl Sci. 2019 Nov;12(6):641-647. doi: 10.1111/cts.12669. Epub 2019 Aug 20. Clin Transl Sci. 2019. PMID: 31350825 Free PMC article.
TP-0903 is active in models of drug-resistant acute myeloid leukemia.
Jeon JY, Buelow DR, Garrison DA, Niu M, Eisenmann ED, Huang KM, Zavorka Thomas ME, Weber RH, Whatcott CJ, Warner SL, Orwick SJ, Carmichael B, Stahl E, Brinton LT, Lapalombella R, Blachly JS, Hertlein E, Byrd JC, Bhatnagar B, Baker SD. Jeon JY, et al. Among authors: buelow dr. JCI Insight. 2020 Dec 3;5(23):e140169. doi: 10.1172/jci.insight.140169. JCI Insight. 2020. PMID: 33268594 Free PMC article.
28 results