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Elevating CDCA3 Levels Enhances Tyrosine Kinase Inhibitor Sensitivity in TKI-Resistant EGFR Mutant Non-Small-Cell Lung Cancer.
Sahin KB, Shah ET, Ferguson GP, Molloy C, Kalita-de Croft P, Hayes SA, Hudson A, Colvin E, Kamitakahara H, Harvie R, Hasovits C, Khan T, Duijf PHG, Howell VM, He Y, Bolderson E, Hooper JD, Lakhani SR, Richard DJ, O'Byrne KJ, Adams MN. Sahin KB, et al. Among authors: adams mn. Cancers (Basel). 2021 Sep 16;13(18):4651. doi: 10.3390/cancers13184651. Cancers (Basel). 2021. PMID: 34572879 Free PMC article.
Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKCdelta.
He Y, Wortmann A, Burke LJ, Reid JC, Adams MN, Abdul-Jabbar I, Quigley JP, Leduc R, Kirchhofer D, Hooper JD. He Y, et al. Among authors: adams mn. J Biol Chem. 2010 Aug 20;285(34):26162-73. doi: 10.1074/jbc.M109.096453. Epub 2010 Jun 15. J Biol Chem. 2010. PMID: 20551327 Free PMC article.
Potent Small Agonists of Protease Activated Receptor 2.
Yau MK, Suen JY, Xu W, Lim J, Liu L, Adams MN, He Y, Hooper JD, Reid RC, Fairlie DP. Yau MK, et al. Among authors: adams mn. ACS Med Chem Lett. 2015 Nov 30;7(1):105-10. doi: 10.1021/acsmedchemlett.5b00429. eCollection 2016 Jan 14. ACS Med Chem Lett. 2015. PMID: 26819675 Free PMC article.
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