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Muscle fibrosis and maladaptation occur progressively in CKD and are rescued by dialysis.
Brightwell CR, Kulkarni AS, Paredes W, Zhang K, Perkins JB, Gatlin KJ, Custodio M, Farooq H, Zaidi B, Pai R, Buttar RS, Tang Y, Melamed ML, Hostetter TH, Pessin JE, Hawkins M, Fry CS, Abramowitz MK. Brightwell CR, et al. Among authors: zhang k. JCI Insight. 2021 Dec 22;6(24):e150112. doi: 10.1172/jci.insight.150112. JCI Insight. 2021. PMID: 34784301 Free PMC article.
Skeletal muscle fibrosis is associated with decreased muscle inflammation and weakness in patients with chronic kidney disease.
Abramowitz MK, Paredes W, Zhang K, Brightwell CR, Newsom JN, Kwon HJ, Custodio M, Buttar RS, Farooq H, Zaidi B, Pai R, Pessin JE, Hawkins M, Fry CS. Abramowitz MK, et al. Among authors: zhang k. Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1658-F1669. doi: 10.1152/ajprenal.00314.2018. Epub 2018 Oct 3. Am J Physiol Renal Physiol. 2018. PMID: 30280599 Free PMC article.
Resveratrol Improves Vascular Function and Mitochondrial Number but Not Glucose Metabolism in Older Adults.
Pollack RM, Barzilai N, Anghel V, Kulkarni AS, Golden A, O'Broin P, Sinclair DA, Bonkowski MS, Coleville AJ, Powell D, Kim S, Moaddel R, Stein D, Zhang K, Hawkins M, Crandall JP. Pollack RM, et al. Among authors: zhang k. J Gerontol A Biol Sci Med Sci. 2017 Nov 9;72(12):1703-1709. doi: 10.1093/gerona/glx041. J Gerontol A Biol Sci Med Sci. 2017. PMID: 28329397 Free PMC article. Clinical Trial.
Central Regulation of Glucose Production May Be Impaired in Type 2 Diabetes.
Esterson YB, Carey M, Boucai L, Goyal A, Raghavan P, Zhang K, Mehta D, Feng D, Wu L, Kehlenbrink S, Koppaka S, Kishore P, Hawkins M. Esterson YB, et al. Among authors: zhang k. Diabetes. 2016 Sep;65(9):2569-79. doi: 10.2337/db15-1465. Epub 2016 May 10. Diabetes. 2016. PMID: 27207526 Free PMC article. Clinical Trial.
Fatty acid-induced production of plasminogen activator inhibitor-1 by adipose macrophages is greater in middle-aged versus younger adult participants.
Esterson YB, Kishore P, Koppaka S, Li W, Zhang K, Tonelli J, Lee DE, Kehlenbrink S, Lawrence S, Crandall J, Barzilai N, Hawkins M. Esterson YB, et al. Among authors: zhang k. J Gerontol A Biol Sci Med Sci. 2012 Dec;67(12):1321-8. doi: 10.1093/gerona/gls200. Epub 2012 Oct 22. J Gerontol A Biol Sci Med Sci. 2012. PMID: 23089338 Free PMC article.
Xylitol prevents NEFA-induced insulin resistance in rats.
Kishore P, Kehlenbrink S, Hu M, Zhang K, Gutierrez-Juarez R, Koppaka S, El-Maghrabi MR, Hawkins M. Kishore P, et al. Among authors: zhang k. Diabetologia. 2012 Jun;55(6):1808-12. doi: 10.1007/s00125-012-2527-z. Epub 2012 Mar 30. Diabetologia. 2012. PMID: 22460760 Free PMC article.
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