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R-loops trigger the release of cytoplasmic ssDNAs leading to chronic inflammation upon DNA damage.
Sci Adv. 2021 Nov 19;7(47):eabj5769. doi: 10.1126/sciadv.abj5769. Epub 2021 Nov 19.
Sci Adv. 2021.
PMID: 34797720
Free PMC article.
DNA damage-induced inflammation and nuclear architecture.
Stratigi K, Chatzidoukaki O, Garinis GA.
Stratigi K, et al. Among authors: chatzidoukaki o.
Mech Ageing Dev. 2017 Jul;165(Pt A):17-26. doi: 10.1016/j.mad.2016.09.008. Epub 2016 Oct 1.
Mech Ageing Dev. 2017.
PMID: 27702596
Review.
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DNA Damage Response and Metabolic Reprogramming in Health and Disease.
Chatzidoukaki O, Goulielmaki E, Schumacher B, Garinis GA.
Chatzidoukaki O, et al.
Trends Genet. 2020 Oct;36(10):777-791. doi: 10.1016/j.tig.2020.06.018. Epub 2020 Jul 17.
Trends Genet. 2020.
PMID: 32684438
Review.
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