Salem R - Search Results

1

Natural inspired ligustrazine-based SLC-0111 analogues as novel carbonic anhydrase inhibitors.

Elimam DM, Eldehna WM, Salem R, Bonardi A, Nocentini A, Al-Rashood ST, Elaasser MM, Gratteri P, Supuran CT, Allam HA. Elimam DM, et al. Among authors: salem r. Eur J Med Chem. 2022 Jan 15;228:114008. doi: 10.1016/j.ejmech.2021.114008. Epub 2021 Nov 27. Eur J Med Chem. 2022. PMID: 34871842

2

Development of novel benzofuran-based SLC-0111 analogs as selective cancer-associated carbonic anhydrase isoform IX inhibitors.

Shaldam M, Eldehna WM, Nocentini A, Elsayed ZM, Ibrahim TM, Salem R, El-Domany RA, Capasso C, Abdel-Aziz HA, Supuran CT. Shaldam M, et al. Among authors: salem r. Eur J Med Chem. 2021 Apr 15;216:113283. doi: 10.1016/j.ejmech.2021.113283. Epub 2021 Feb 18. Eur J Med Chem. 2021. PMID: 33667848

3

Development of novel benzofuran-isatin conjugates as potential antiproliferative agents with apoptosis inducing mechanism in Colon cancer.

Eldehna WM, Salem R, Elsayed ZM, Al-Warhi T, Knany HR, Ayyad RR, Traiki TB, Abdulla MH, Ahmad R, Abdel-Aziz HA, El-Haggar R. Eldehna WM, et al. Among authors: salem r. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1424-1435. doi: 10.1080/14756366.2021.1944127. J Enzyme Inhib Med Chem. 2021. PMID: 34176414 Free PMC article.

4

Development of Novel Quinoline-Based Sulfonamides as Selective Cancer-Associated Carbonic Anhydrase Isoform IX Inhibitors.

Shaldam M, Nocentini A, Elsayed ZM, Ibrahim TM, Salem R, El-Domany RA, Capasso C, Supuran CT, Eldehna WM. Shaldam M, et al. Among authors: salem r. Int J Mol Sci. 2021 Oct 15;22(20):11119. doi: 10.3390/ijms222011119. Int J Mol Sci. 2021. PMID: 34681794 Free PMC article.

5

Novel 3-(6-methylpyridin-2-yl)coumarin-based chalcones as selective inhibitors of cancer-related carbonic anhydrases IX and XII endowed with anti-proliferative activity.

Tawfik HO, Shaldam MA, Nocentini A, Salem R, Almahli H, Al-Rashood ST, Supuran CT, Eldehna WM. Tawfik HO, et al. Among authors: salem r. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1043-1052. doi: 10.1080/14756366.2022.2056734. J Enzyme Inhib Med Chem. 2022. PMID: 35437108 Free PMC article.

6

Identification of novel piperazine-tethered phthalazines as selective CDK1 inhibitors endowed with in vitro anticancer activity toward the pancreatic cancer.

Akl L, Abd El-Hafeez AA, Ibrahim TM, Salem R, Marzouk HMM, El-Domany RA, Ghosh P, Eldehna WM, Abou-Seri SM. Akl L, et al. Among authors: salem r. Eur J Med Chem. 2022 Dec 5;243:114704. doi: 10.1016/j.ejmech.2022.114704. Epub 2022 Aug 31. Eur J Med Chem. 2022. PMID: 36095992

7

Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors.

Shaldam MA, Almahli H, Angeli A, Badi RM, Khaleel EF, Zain-Alabdeen AI, Elsayed ZM, Elkaeed EB, Salem R, Supuran CT, Eldehna WM, Tawfik HO. Shaldam MA, et al. Among authors: salem r. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2203389. doi: 10.1080/14756366.2023.2203389. J Enzyme Inhib Med Chem. 2023. PMID: 37122176 Free PMC article.

8

Tetrahydrobenzo[h]quinoline derivatives as a novel chemotype for dual antileishmanial-antimalarial activity graced with antitubercular activity: Design, synthesis and biological evaluation.

Ibrahim TM, Abada G, Dammann M, Maklad RM, Eldehna WM, Salem R, Abdelaziz MM, El-Domany RA, Bekhit AA, Beockler FM. Ibrahim TM, et al. Among authors: salem r. Eur J Med Chem. 2023 Sep 5;257:115534. doi: 10.1016/j.ejmech.2023.115534. Epub 2023 May 29. Eur J Med Chem. 2023. PMID: 37269671

9

1,5-Diaryl-1,2,4-triazole Ureas as New SLC-0111 Analogues Endowed with Dual Carbonic Anhydrase and VEGFR-2 Inhibitory Activities.

Elsawi AE, Elbadawi MM, Nocentini A, Almahli H, Giovannuzzi S, Shaldam M, Salem R, Ibrahim TM, Abdel-Aziz HA, Supuran CT, Eldehna WM. Elsawi AE, et al. Among authors: salem r. J Med Chem. 2023 Aug 10;66(15):10558-10578. doi: 10.1021/acs.jmedchem.3c00721. Epub 2023 Jul 27. J Med Chem. 2023. PMID: 37501287

10

Discovery of indolinone-bearing benzenesulfonamides as new dual carbonic anhydrase and VEGFR-2 inhibitors possessing anticancer and pro-apoptotic properties.

Saied S, Shaldam M, Elbadawi MM, Giovannuzzi S, Nocentini A, Almahli H, Salem R, Ibrahim TM, Supuran CT, Eldehna WM. Saied S, et al. Among authors: salem r. Eur J Med Chem. 2023 Nov 5;259:115707. doi: 10.1016/j.ejmech.2023.115707. Epub 2023 Aug 2. Eur J Med Chem. 2023. PMID: 37556946

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