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Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth.
Müller M, Gerndt S, Chao YK, Zisis T, Nguyen ONP, Gerwien A, Urban N, Müller C, Gegenfurtner FA, Geisslinger F, Ortler C, Chen CC, Zahler S, Biel M, Schaefer M, Grimm C, Bracher F, Vollmar AM, Bartel K. Müller M, et al. Among authors: zisis t. Cell Chem Biol. 2021 Aug 19;28(8):1119-1131.e27. doi: 10.1016/j.chembiol.2021.01.023. Epub 2021 Feb 23. Cell Chem Biol. 2021. PMID: 33626324 Free article.
Transcriptional effects of actin-binding compounds: the cytoplasm sets the tone.
Gegenfurtner FA, Zisis T, Al Danaf N, Schrimpf W, Kliesmete Z, Ziegenhain C, Enard W, Kazmaier U, Lamb DC, Vollmar AM, Zahler S. Gegenfurtner FA, et al. Among authors: zisis t. Cell Mol Life Sci. 2018 Dec;75(24):4539-4555. doi: 10.1007/s00018-018-2919-4. Epub 2018 Sep 11. Cell Mol Life Sci. 2018. PMID: 30206640 Free PMC article.
Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy.
Pfitzer L, Moser C, Gegenfurtner F, Arner A, Foerster F, Atzberger C, Zisis T, Kubisch-Dohmen R, Busse J, Smith R, Timinszky G, Kalinina OV, Müller R, Wagner E, Vollmar AM, Zahler S. Pfitzer L, et al. Among authors: zisis t. Cell Death Dis. 2019 Apr 3;10(4):302. doi: 10.1038/s41419-019-1546-9. Cell Death Dis. 2019. PMID: 30944311 Free PMC article.
Tetrapyrrolic Pigments from Heme- and Chlorophyll Breakdown are Actin-Targeting Compounds.
Karg CA, Wang S, Al Danaf N, Pemberton RP, Bernard D, Kretschmer M, Schneider S, Zisis T, Vollmar AM, Lamb DC, Zahler S, Moser S. Karg CA, et al. Among authors: zisis t. Angew Chem Int Ed Engl. 2021 Oct 4;60(41):22578-22584. doi: 10.1002/anie.202107813. Epub 2021 Aug 31. Angew Chem Int Ed Engl. 2021. PMID: 34310831 Free PMC article.
Affinity-Based Purification of Polyisocyanopeptide Bioconjugates.
Hammink R, Eggermont LJ, Zisis T, Tel J, Figdor CG, Rowan AE, Blank KG. Hammink R, et al. Among authors: zisis t. Bioconjug Chem. 2017 Oct 18;28(10):2560-2568. doi: 10.1021/acs.bioconjchem.7b00398. Epub 2017 Sep 15. Bioconjug Chem. 2017. PMID: 28846388