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Review of pragmatic trials found that multiple primary outcomes are common but so too are discrepancies between protocols and final reports.
Nevins P, Vanderhout S, Carroll K, Nicholls SG, Semchishen SN, Brehaut JC, Fergusson DA, Giraudeau B, Taljaard M. Nevins P, et al. Among authors: semchishen sn. J Clin Epidemiol. 2022 Mar;143:149-158. doi: 10.1016/j.jclinepi.2021.12.006. Epub 2021 Dec 8. J Clin Epidemiol. 2022. PMID: 34896234 Free PMC article. Review.
Chronic sleep disruption induces depression-like behavior in adolescent male and female mice and sensitization of the hypothalamic-pituitary-adrenal axis in adolescent female mice.
Murack M, Chandrasegaram R, Smith KB, Ah-Yen EG, Rheaume É, Malette-Guyon É, Nanji Z, Semchishen SN, Latus O, Messier C, Ismail N. Murack M, et al. Among authors: semchishen sn. Behav Brain Res. 2021 Feb 5;399:113001. doi: 10.1016/j.bbr.2020.113001. Epub 2020 Nov 13. Behav Brain Res. 2021. PMID: 33197456