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Histone deacetylases inhibitors as new potential drugs against Leishmania braziliensis, the main causative agent of new world tegumentary leishmaniasis.
Ângelo de Souza L, Silva E Bastos M, de Melo Agripino J, Souza Onofre T, Apaza Calla LF, Heimburg T, Ghazy E, Bayer T, Ferraz da Silva VH, Dutra Ribeiro P, Licursi de Oliveira L, Costa Bressan G, de Almeida Lamêgo MR, Silva-Júnior A, de Souza Vasconcellos R, Suarez-Fontes AM, Almeida-Silva J, Vannier-Santos MA, Pierce R, Sippl W, Lopes Rangel Fietto J. Ângelo de Souza L, et al. Biochem Pharmacol. 2020 Oct;180:114191. doi: 10.1016/j.bcp.2020.114191. Epub 2020 Aug 7. Biochem Pharmacol. 2020. PMID: 32777278
Leishmania infantum ecto-nucleoside triphosphate diphosphohydrolase-2 is an apyrase involved in macrophage infection and expressed in infected dogs.
Vasconcellos Rde S, Mariotini-Moura C, Gomes RS, Serafim TD, Firmino Rde C, Silva E Bastos M, Castro FF, Oliveira CM, Borges-Pereira L, de Souza AC, de Souza RF, Gómez GA, Pinheiro Ada C, Maciel TE, Silva-Júnior A, Bressan GC, Almeida MR, Baqui MM, Afonso LC, Fietto JL. Vasconcellos Rde S, et al. PLoS Negl Trop Dis. 2014 Nov 13;8(11):e3309. doi: 10.1371/journal.pntd.0003309. eCollection 2014 Nov. PLoS Negl Trop Dis. 2014. PMID: 25393008 Free PMC article.
298 results