de Graaf N - Search Results

1

Single-Cell Transcriptomics Links Loss of Human Pancreatic β-Cell Identity to ER Stress.

Groen N, Leenders F, Mahfouz A, Munoz-Garcia A, Muraro MJ, de Graaf N, Rabelink TJ, Hoeben R, van Oudenaarden A, Zaldumbide A, Reinders MJT, Koning EJP, Carlotti F. Groen N, et al. Among authors: de graaf n. Cells. 2021 Dec 19;10(12):3585. doi: 10.3390/cells10123585. Cells. 2021. PMID: 34944092 Free PMC article.

2

Topologically heterogeneous beta cell adaptation in response to high-fat diet in mice.

Ellenbroek JH, Töns HA, de Graaf N, Loomans CJ, Engelse MA, Vrolijk H, Voshol PJ, Rabelink TJ, Carlotti F, de Koning EJ. Ellenbroek JH, et al. Among authors: de graaf n, de koning ej. PLoS One. 2013;8(2):e56922. doi: 10.1371/journal.pone.0056922. Epub 2013 Feb 18. PLoS One. 2013. PMID: 23441226 Free PMC article.

3

Glucagon-like peptide-1 receptor agonist treatment reduces beta cell mass in normoglycaemic mice.

Ellenbroek JH, Töns HA, Westerouen van Meeteren MJ, de Graaf N, Hanegraaf MA, Rabelink TJ, Carlotti F, de Koning EJ. Ellenbroek JH, et al. Among authors: de graaf n, de koning ej. Diabetologia. 2013 Sep;56(9):1980-6. doi: 10.1007/s00125-013-2957-2. Epub 2013 Jun 16. Diabetologia. 2013. PMID: 23771206

4

Highly efficient ex vivo lentiviral transduction of primary human pancreatic exocrine cells.

Balak JRA, de Graaf N, Zaldumbide A, Rabelink TJ, Hoeben RC, de Koning EJP, Carlotti F. Balak JRA, et al. Among authors: de koning ejp, de graaf n. Sci Rep. 2019 Nov 1;9(1):15870. doi: 10.1038/s41598-019-51763-z. Sci Rep. 2019. PMID: 31676849 Free PMC article.

5

Oxidative Stress Leads to β-Cell Dysfunction Through Loss of β-Cell Identity.

Leenders F, Groen N, de Graaf N, Engelse MA, Rabelink TJ, de Koning EJP, Carlotti F. Leenders F, et al. Among authors: de koning ejp, de graaf n. Front Immunol. 2021 Nov 4;12:690379. doi: 10.3389/fimmu.2021.690379. eCollection 2021. Front Immunol. 2021. PMID: 34804002 Free PMC article.

6

Apolipoprotein L genes are novel mediators of inflammation in beta cells.

Paz-Barba M, Muñoz Garcia A, de Winter TJJ, de Graaf N, van Agen M, van der Sar E, Lambregtse F, Daleman L, van der Slik A, Zaldumbide A, de Koning EJP, Carlotti F. Paz-Barba M, et al. Among authors: de graaf n. Diabetologia. 2024 Jan;67(1):124-136. doi: 10.1007/s00125-023-06033-z. Epub 2023 Nov 4. Diabetologia. 2024. PMID: 37924378 Free PMC article.

7

[No title available]

[No authors listed] [No authors listed] PMID: 34908362

8

The bone marrow functions as the central site of proliferation for long-lived NK cells.

van Helden MJ, de Graaf N, Boog CJ, Topham DJ, Zaiss DM, Sijts AJ. van Helden MJ, et al. Among authors: de graaf n. J Immunol. 2012 Sep 1;189(5):2333-7. doi: 10.4049/jimmunol.1200008. Epub 2012 Jul 20. J Immunol. 2012. PMID: 22821961 Free PMC article.

9

PA28 and the proteasome immunosubunits play a central and independent role in the production of MHC class I-binding peptides in vivo.

de Graaf N, van Helden MJ, Textoris-Taube K, Chiba T, Topham DJ, Kloetzel PM, Zaiss DM, Sijts AJ. de Graaf N, et al. Eur J Immunol. 2011 Apr;41(4):926-35. doi: 10.1002/eji.201041040. Epub 2011 Mar 1. Eur J Immunol. 2011. PMID: 21360704 Free PMC article.

10

Immunoproteasome-deficiency has no effects on NK cell education, but confers lymphocytes into targets for NK cells in infected wild-type mice.

van Helden MJ, de Graaf N, Bekker CP, Boog CJ, Zaiss DM, Sijts AJ. van Helden MJ, et al. Among authors: de graaf n. PLoS One. 2011;6(8):e23769. doi: 10.1371/journal.pone.0023769. Epub 2011 Aug 24. PLoS One. 2011. PMID: 21887316 Free PMC article.

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