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Unadjuvanted intranasal spike vaccine booster elicits robust protective mucosal immunity against sarbecoviruses.
Mao T, Israelow B, Suberi A, Zhou L, Reschke M, Peña-Hernández MA, Dong H, Homer RJ, Saltzman WM, Iwasaki A. Mao T, et al. Among authors: dong h. bioRxiv [Preprint]. 2022 Jan 26:2022.01.24.477597. doi: 10.1101/2022.01.24.477597. bioRxiv. 2022. Update in: Science. 2022 Nov 25;378(6622):eabo2523. doi: 10.1126/science.abo2523. PMID: 35118464 Free PMC article. Updated. Preprint.
Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.
Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, Alfajaro MM, Wei J, Dong H, Homer RJ, Ring A, Wilen CB, Iwasaki A. Israelow B, et al. Among authors: dong h. bioRxiv [Preprint]. 2020 May 27:2020.05.27.118893. doi: 10.1101/2020.05.27.118893. bioRxiv. 2020. Update in: J Exp Med. 2020 Dec 7;217(12):e20201241. doi: 10.1084/jem.20201241. PMID: 32577647 Free PMC article. Updated. Preprint.
A stem-loop RNA RIG-I agonist confers prophylactic and therapeutic protection against acute and chronic SARS-CoV-2 infection in mice.
Mao T, Israelow B, Lucas C, Vogels CBF, Fedorova O, Breban MI, Menasche BL, Dong H, Linehan M; Yale SARS-CoV-2 Genome Surveillance Initiative; Wilen CB, Landry ML, Grubaugh ND, Pyle AM, Iwasaki A. Mao T, et al. Among authors: dong h. bioRxiv [Preprint]. 2021 Jun 17:2021.06.16.448754. doi: 10.1101/2021.06.16.448754. bioRxiv. 2021. Update in: J Exp Med. 2022 Jan 3;219(1):e20211818. doi: 10.1084/jem.20211818. PMID: 34159330 Free PMC article. Updated. Preprint.
A stem-loop RNA RIG-I agonist protects against acute and chronic SARS-CoV-2 infection in mice.
Mao T, Israelow B, Lucas C, Vogels CBF, Gomez-Calvo ML, Fedorova O, Breban MI, Menasche BL, Dong H, Linehan M; Yale SARS-CoV-2 Genome Surveillance Initiative; Wilen CB, Landry ML, Grubaugh ND, Pyle AM, Iwasaki A. Mao T, et al. Among authors: dong h. J Exp Med. 2022 Jan 3;219(1):e20211818. doi: 10.1084/jem.20211818. Epub 2021 Nov 10. J Exp Med. 2022. PMID: 34757384 Free PMC article.
Intranasal neomycin evokes broad-spectrum antiviral immunity in the upper respiratory tract.
Mao T, Kim J, Peña-Hernández MA, Valle G, Moriyama M, Luyten S, Ott IM, Gomez-Calvo ML, Gehlhausen JR, Baker E, Israelow B, Slade M, Sharma L, Liu W, Ryu C, Korde A, Lee CJ, Silva Monteiro V, Lucas C, Dong H, Yang Y; Yale SARS-CoV-2 Genomic Surveillance Initiative; Gopinath S, Wilen CB, Palm N, Dela Cruz CS, Iwasaki A. Mao T, et al. Among authors: dong h. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2319566121. doi: 10.1073/pnas.2319566121. Epub 2024 Apr 22. Proc Natl Acad Sci U S A. 2024. PMID: 38648490 Free PMC article.
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