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Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents.
Grillo A, Fezza F, Chemi G, Colangeli R, Brogi S, Fazio D, Federico S, Papa A, Relitti N, Di Maio R, Giorgi G, Lamponi S, Valoti M, Gorelli B, Saponara S, Benedusi M, Pecorelli A, Minetti P, Valacchi G, Butini S, Campiani G, Gemma S, Maccarrone M, Di Giovanni G. Grillo A, et al. Among authors: papa a. ACS Chem Neurosci. 2021 May 5;12(9):1716-1736. doi: 10.1021/acschemneuro.1c00192. Epub 2021 Apr 23. ACS Chem Neurosci. 2021. PMID: 33890763
Design and Synthesis of Oligopeptidic Parvulin Inhibitors.
Relitti N, Prasanth Saraswati A, Carullo G, Papa A, Monti A, Benedetti R, Passaro E, Brogi S, Calderone V, Butini S, Gemma S, Altucci L, Campiani G, Doti N. Relitti N, et al. Among authors: papa a. ChemMedChem. 2022 Jun 3;17(11):e202200050. doi: 10.1002/cmdc.202200050. Epub 2022 Apr 26. ChemMedChem. 2022. PMID: 35357776 Free PMC article.
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability.
Federico S, Khan T, Fontana A, Brogi S, Benedetti R, Sarno F, Carullo G, Pezzotta A, Saraswati AP, Passaro E, Pozzetti L, Papa A, Relitti N, Gemma S, Butini S, Pistocchi A, Ramunno A, Vincenzi F, Varani K, Tatangelo V, Patrussi L, Baldari CT, Saponara S, Gorelli B, Lamponi S, Valoti M, Saccoccia F, Giannaccari M, Ruberti G, Herp D, Jung M, Altucci L, Campiani G. Federico S, et al. Among authors: papa a. Eur J Med Chem. 2022 Aug 5;238:114409. doi: 10.1016/j.ejmech.2022.114409. Epub 2022 May 1. Eur J Med Chem. 2022. PMID: 35551034
Synthesis of Unsymmetrical Squaramides as Allosteric GSK-3β Inhibitors Promoting β-Catenin-Mediated Transcription of TCF/LEF in Retinal Pigment Epithelial Cells.
Carullo G, Bottoni L, Pasquini S, Papa A, Contri C, Brogi S, Calderone V, Orlandini M, Gemma S, Varani K, Butini S, Galvagni F, Vincenzi F, Campiani G. Carullo G, et al. Among authors: papa a. ChemMedChem. 2022 Dec 16;17(24):e202200456. doi: 10.1002/cmdc.202200456. Epub 2022 Oct 27. ChemMedChem. 2022. PMID: 36194001
Development of potent and selective FAAH inhibitors with improved drug-like properties as potential tools to treat neuroinflammatory conditions.
Papa A, Pasquini S, Galvani F, Cammarota M, Contri C, Carullo G, Gemma S, Ramunno A, Lamponi S, Gorelli B, Saponara S, Varani K, Mor M, Campiani G, Boscia F, Vincenzi F, Lodola A, Butini S. Papa A, et al. Eur J Med Chem. 2023 Jan 15;246:114952. doi: 10.1016/j.ejmech.2022.114952. Epub 2022 Nov 25. Eur J Med Chem. 2023. PMID: 36462439
Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization.
Butini S, Grether U, Jung KM, Ligresti A, Allarà M, Postmus AGJ, Maramai S, Brogi S, Papa A, Carullo G, Sykes D, Veprintsev D, Federico S, Grillo A, Di Guglielmo B, Ramunno A, Stevens AF, Heer D, Lamponi S, Gemma S, Benz J, Di Marzo V, van der Stelt M, Piomelli D, Campiani G. Butini S, et al. Among authors: papa a. J Med Chem. 2024 Feb 8;67(3):1758-1782. doi: 10.1021/acs.jmedchem.3c01278. Epub 2024 Jan 19. J Med Chem. 2024. PMID: 38241614
Asymmetric allostery in estrogen receptor-α homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Min CK, Nwachukwu JC, Hou Y, Russo RJ, Papa A, Min J, Peng R, Kim SH, Ziegler Y, Rangarajan ES, Izard T, Katzenellenbogen BS, Katzenellenbogen JA, Nettles KW. Min CK, et al. Among authors: papa a. Proc Natl Acad Sci U S A. 2024 Jun 11;121(24):e2321344121. doi: 10.1073/pnas.2321344121. Epub 2024 Jun 3. Proc Natl Acad Sci U S A. 2024. PMID: 38830107
1,021 results