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Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics.
Bhatia S, Kramer M, Russo S, Naik P, Arun G, Brophy K, Andrews P, Fan C, Perou CM, Preall J, Ha T, Plenker D, Tuveson DA, Rishi A, Wilkinson JE, McCombie WR, Kostroff K, Spector DL. Bhatia S, et al. Among authors: wilkinson je. Cancer Res. 2022 Apr 1;82(7):1174-1192. doi: 10.1158/0008-5472.CAN-21-2807. Cancer Res. 2022. PMID: 35180770 Free PMC article.
MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2.
Nowak DG, Cho H, Herzka T, Watrud K, DeMarco DV, Wang VM, Senturk S, Fellmann C, Ding D, Beinortas T, Kleinman D, Chen M, Sordella R, Wilkinson JE, Castillo-Martin M, Cordon-Cardo C, Robinson BD, Trotman LC. Nowak DG, et al. Among authors: wilkinson je. Cancer Discov. 2015 Jun;5(6):636-51. doi: 10.1158/2159-8290.CD-14-1113. Epub 2015 Mar 31. Cancer Discov. 2015. PMID: 25829425 Free PMC article.
A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis.
Wagenblast E, Soto M, Gutiérrez-Ángel S, Hartl CA, Gable AL, Maceli AR, Erard N, Williams AM, Kim SY, Dickopf S, Harrell JC, Smith AD, Perou CM, Wilkinson JE, Hannon GJ, Knott SR. Wagenblast E, et al. Among authors: wilkinson je. Nature. 2015 Apr 16;520(7547):358-62. doi: 10.1038/nature14403. Epub 2015 Apr 8. Nature. 2015. PMID: 25855289 Free PMC article.
ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms.
Palmbos PL, Wang L, Yang H, Wang Y, Leflein J, Ahmet ML, Wilkinson JE, Kumar-Sinha C, Ney GM, Tomlins SA, Daignault S, Kunju LP, Wu XR, Lotan Y, Liebert M, Ljungman ME, Simeone DM. Palmbos PL, et al. Among authors: wilkinson je. Cancer Res. 2015 Dec 1;75(23):5155-66. doi: 10.1158/0008-5472.CAN-15-0603. Epub 2015 Oct 15. Cancer Res. 2015. PMID: 26471361 Free PMC article.
Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss.
Arun G, Diermeier S, Akerman M, Chang KC, Wilkinson JE, Hearn S, Kim Y, MacLeod AR, Krainer AR, Norton L, Brogi E, Egeblad M, Spector DL. Arun G, et al. Among authors: wilkinson je. Genes Dev. 2016 Jan 1;30(1):34-51. doi: 10.1101/gad.270959.115. Epub 2015 Dec 23. Genes Dev. 2016. PMID: 26701265 Free PMC article.
NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.
Chio IIC, Jafarnejad SM, Ponz-Sarvise M, Park Y, Rivera K, Palm W, Wilson J, Sangar V, Hao Y, Öhlund D, Wright K, Filippini D, Lee EJ, Da Silva B, Schoepfer C, Wilkinson JE, Buscaglia JM, DeNicola GM, Tiriac H, Hammell M, Crawford HC, Schmidt EE, Thompson CB, Pappin DJ, Sonenberg N, Tuveson DA. Chio IIC, et al. Among authors: wilkinson je. Cell. 2016 Aug 11;166(4):963-976. doi: 10.1016/j.cell.2016.06.056. Epub 2016 Jul 28. Cell. 2016. PMID: 27477511 Free PMC article.
Asparagine bioavailability governs metastasis in a model of breast cancer.
Knott SRV, Wagenblast E, Khan S, Kim SY, Soto M, Wagner M, Turgeon MO, Fish L, Erard N, Gable AL, Maceli AR, Dickopf S, Papachristou EK, D'Santos CS, Carey LA, Wilkinson JE, Harrell JC, Perou CM, Goodarzi H, Poulogiannis G, Hannon GJ. Knott SRV, et al. Among authors: wilkinson je. Nature. 2018 Feb 15;554(7692):378-381. doi: 10.1038/nature25465. Epub 2018 Feb 7. Nature. 2018. PMID: 29414946 Free PMC article.
POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer.
Huang YH, Klingbeil O, He XY, Wu XS, Arun G, Lu B, Somerville TDD, Milazzo JP, Wilkinson JE, Demerdash OE, Spector DL, Egeblad M, Shi J, Vakoc CR. Huang YH, et al. Among authors: wilkinson je. Genes Dev. 2018 Jul 1;32(13-14):915-928. doi: 10.1101/gad.314815.118. Epub 2018 Jun 26. Genes Dev. 2018. PMID: 29945888 Free PMC article.
228 results