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N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases.
Kaya C, Konstantinović J, Kany AM, Andreas A, Kramer JS, Brunst S, Weizel L, Rotter MJ, Frank D, Yahiaoui S, Müller R, Hartmann RW, Haupenthal J, Proschak E, Wichelhaus TA, Hirsch AKH. Kaya C, et al. Among authors: yahiaoui s. J Med Chem. 2022 Mar 10;65(5):3913-3922. doi: 10.1021/acs.jmedchem.1c01755. Epub 2022 Feb 21. J Med Chem. 2022. PMID: 35188771
N-Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases.
Konstantinović J, Yahiaoui S, Alhayek A, Haupenthal J, Schönauer E, Andreas A, Kany AM, Müller R, Koehnke J, Berger FK, Bischoff M, Hartmann RW, Brandstetter H, Hirsch AKH. Konstantinović J, et al. Among authors: yahiaoui s. J Med Chem. 2020 Aug 13;63(15):8359-8368. doi: 10.1021/acs.jmedchem.0c00584. Epub 2020 Jun 17. J Med Chem. 2020. PMID: 32470298 Free PMC article.
Semisynthesis and biological evaluation of amidochelocardin derivatives as broad-spectrum antibiotics.
Grandclaudon C, Birudukota NVS, Elgaher WAM, Jumde RP, Yahiaoui S, Arisetti N, Hennessen F, Hüttel S, Stadler M, Herrmann J, Miethke M, Hartmann RW, Müller R, Hirsch AKH, Brönstrup M. Grandclaudon C, et al. Among authors: yahiaoui s. Eur J Med Chem. 2020 Feb 15;188:112005. doi: 10.1016/j.ejmech.2019.112005. Epub 2019 Dec 20. Eur J Med Chem. 2020. PMID: 31911294
Substrate-Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors.
Kaya C, Walter I, Yahiaoui S, Sikandar A, Alhayek A, Konstantinović J, Kany AM, Haupenthal J, Köhnke J, Hartmann RW, Hirsch AKH. Kaya C, et al. Among authors: yahiaoui s. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112295. doi: 10.1002/anie.202112295. Epub 2021 Dec 13. Angew Chem Int Ed Engl. 2022. PMID: 34762767 Free PMC article.
A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms.
Schütz C, Ho DK, Hamed MM, Abdelsamie AS, Röhrig T, Herr C, Kany AM, Rox K, Schmelz S, Siebenbürger L, Wirth M, Börger C, Yahiaoui S, Bals R, Scrima A, Blankenfeldt W, Horstmann JC, Christmann R, Murgia X, Koch M, Berwanger A, Loretz B, Hirsch AKH, Hartmann RW, Lehr CM, Empting M. Schütz C, et al. Among authors: yahiaoui s. Adv Sci (Weinh). 2021 Jun;8(12):e2004369. doi: 10.1002/advs.202004369. Epub 2021 Mar 18. Adv Sci (Weinh). 2021. PMID: 34165899 Free PMC article.
58 results