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The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy responses.
Li Z, Jiao X, Robertson AG, Di Sante G, Ashton AW, DiRocco A, Wang M, Zhao J, Addya S, Wang C, McCue PA, South AP, Cordon-Cardo C, Liu R, Patel K, Hamid R, Parmar J, DuHadaway JB, Jones SJM, Casimiro MC, Schultz N, Kossenkov A, Phoon LY, Chen H, Lan L, Sun Y, Iczkowski KA, Rui H, Pestell RG. Li Z, et al. Among authors: phoon ly. Oncogene. 2023 Jun;42(22):1857-1873. doi: 10.1038/s41388-023-02668-9. Epub 2023 Apr 24. Oncogene. 2023. PMID: 37095257 Free PMC article.
The RNA m5C modification in R-loops as an off switch of Alt-NHEJ.
Yang H, Lachtara EM, Ran X, Hopkins J, Patel PS, Zhu X, Xiao Y, Phoon L, Gao B, Zou L, Lawrence MS, Lan L. Yang H, et al. Among authors: phoon l. Nat Commun. 2023 Sep 30;14(1):6114. doi: 10.1038/s41467-023-41790-w. Nat Commun. 2023. PMID: 37777505 Free PMC article.
The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy responses.
Li Z, Jiao X, Robertson AG, Sante GD, Ashton AW, DiRocco A, Wang M, Zhao J, Addya S, Wang C, McCue PA, South AP, Cordon-Cardo C, Liu R, Patel K, Hamid R, Parmar J, DuHadaway JB, Jones SJ, Casimiro MC, Schultz N, Kossenkov A, Phoon LY, Chen H, Lan L, Sun Y, Iczkowski KA, Rui H, Pestell RG. Li Z, et al. Among authors: phoon ly. Res Sq [Preprint]. 2023 Jan 10:rs.3.rs-2423179. doi: 10.21203/rs.3.rs-2423179/v1. Res Sq. 2023. PMID: 36712010 Free PMC article. Updated. Preprint.